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Audit: QRS - Artichoke Extract for Health & Longevity

Audit conducted on 22/06/2026 06:11 using AI4L / Opus 4.8

Iterations

Summary

Items Count
Total 91
Passed 84
Failed 0
N/A 7
Pass Rate 100.00%
  • Total = Passed + Failed + N/A
  • Pass Rate = Passed / (Passed + Failed) × 100
  • N/A items are excluded from the pass rate calculation

1. General Rules

# Description Result Comments
1.1 Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. 🟢 All QRS content traces to the ER (protocol, benefits, risks, monitoring, at-a-glance).
1.2 Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. 🟢 Cautious tiering and “theoretical”/”speculative” framing preserved.
1.3 The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). 🟢 No strengthening/softening detected; pregnancy carried as contraindication consistent with ER.
1.4 The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. 🟢 Categories map faithfully: contraindications, interactions, benefits, risks, monitoring.
1.5 PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. 🟢 No citations, NCT IDs, expert names, or brands appear in the QRS.
1.6 The QRS does not introduce new attributions. 🟢 No attributions introduced.

2. Focus, Tone & Audience

# Description Result Comments
2.1 The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. 🟢 Tone matches the measured, evidence-anchored ER voice.
2.2 The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging 🟢 Tone is expert yet accessible and objective.
2.3 The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor 🟢 Presents evidence, not directives.
2.4 The QRS avoids language that implies medical or clinical advice 🟢 No prescriptive/advisory language.
2.5 The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” 🟢 Information-presenting throughout.
2.6 The QRS never addresses “the reader” directly — it presents evidence, not guidance 🟢 No second-person address.
2.7 The QRS is written in plain language, avoiding unnecessary medical jargon 🟢 Plain language; technical terms minimal and clear.
2.8 Information is presented in a concise and very compact manner 🟢 Compact cells and lists.
2.9 It DOES NOT address the reader directly 🟢 No direct address.
2.10 The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. 🟢 Framing targets proactive, longevity-oriented adults.
2.11 The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. 🟢 Protocol/monitoring framing assumes a willing, proactive reader.
2.12 The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. 🟢 Not pitched to the general population.
2.13 Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. 🟢 Weighting reflects the optimization-oriented audience.
2.14 The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” are quoted verbatim. 🟢 Uses “Health & Longevity”; no “anti-aging” usage.
2.15 The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. 🟢 Formal terminology; “bad” cholesterol and “blood sugar” mirror the ER’s own register.

3. Template Integrity

# Description Result Comments
3.1 The following labels and headings on the QRS are fixed and not modified (card/section headings, gate headings, tier labels, Monitoring table column headers). 🟢 All fixed headings/labels intact (“Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”, “Contraindications”, “Key Interactions”, tiers, “Marker”/”Target”/”Why”).
3.2 All “…” from the [qrs_template] are present in the QRS. 🟢 All template spans present (header, at_a_glance, action/time 1–3, benefits, risks, stop/caution, 7 markers, cadence, 3 qualitative).
3.3 Spans that are not addressed in a checklist item are left unchanged 🟢 page_title and other structural spans unchanged.

4. Formatting

# Description Result Comments
4.1 When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. 🟢 No empty source sections required empty-state phrasing; all populated sections have content.
4.2 Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. 🟢 Protocol/time labels (Dose, Form, Timing, Lipids, Digestion) align with ER content.
4.3 Labels are not paraphrased, abbreviated, or invented. 🟢 Labels faithful to ER.
4.4 The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). 🟢 No emoji indicators in QRS; tiers conveyed via bold labels/CSS.
4.5 The QRS is designed to render on one A4 page. Any section with more ER content than fits is condensed by the LLM, not extended onto a second page. 🟢 Content condensed to single-page budget.

5. Metadata

# Description Result Comments
5.1 The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. 🟢 Metadata comment is first element after doctype.
5.2 Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. 🟢 YAML delimited by — / —.
5.3 The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. 🟢 Enclosed in HTML comment; not rendered.
5.4 All frontmatter values are trimmed: no leading/trailing whitespace, no surrounding quotes unless required by YAML. 🟢 Values trimmed; only duration quoted (contains colon).
5.5 The filename of the source ER is stated as “er_filename: [er_filename]” 🟢 er_filename: artichoke_extract_2026-0622-0517_Opus_ER.md.
5.6 Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” 🟢 qrs_prompt_version: 26.5.18 matches QRS.md.
5.7 Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” 🟢 qrs_creation_date: 2026-0622-0517.
5.8 The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” 🟢 qrs_creator_ai_nickname: Opus.
5.9 The nickname of the AI is just a single word model name without version, etc. 🟢 “Opus” — single word.
5.10 The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” 🟢 qrs_creator_ai_fullname: Opus 4.8.
5.11 The full name of the AI consists of the nickname and the model version number and no additional qualifier. 🟢 “Opus 4.8” — nickname + version.
5.12 The filename of the document is stated as “qrs_filename: [filename of this document]” 🟢 qrs_filename: artichoke_extract_2026-0622-0517_Opus_QRS.html.
5.13 All frontmatter values are trimmed: no leading/trailing whitespace, no surrounding quotes unless required by YAML. 🟢 Consistent and trimmed.

6. Page Title & Header

# Description Result Comments
6.1 [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet”, HTML-entity-encoded as needed. 🟢 “Artichoke Extract for Health & Longevity - Quick Reference Sheet”.
6.2 [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed. 🟢 “Artichoke Extract for Health & Longevity”.
6.3 [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] 🟢 “06/22/2026” from 2026-0622.
6.4 [header_subline_model] is set to [qrs_creator_ai_fullname] 🟢 “Opus 4.8”.
6.5 No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. 🟢 Header contains only date, ER reference, AI4L, and model.

7. At-A-Glance Section

# Description Result Comments
7.1 [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section 🟢 Condenses the Conclusion (lipids, liver, weak signals, magnitude, tolerability).
7.2 [at_a_glance] is no longer than 60 words 🟢 52 words.
7.3 Every fact in [at_a_glance] is supported by a distinct passage in the ER. 🟢 Each claim traces to the Conclusion.
7.4 It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead 🟢 Plain language (“bad” cholesterol, blood sugar); no acronyms.
7.5 It DOES NOT cite specific trials (names, years, sample sizes, p-values) 🟢 No trial citations.
7.6 It DOES NOT cite effect sizes, relative risks, or statistical results 🟢 No effect sizes or statistics.

8. Contraindications

# Description Result Comments
8.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Drawn from “Populations who should avoid”.
8.2 [stop_items] represent the Contraindications from the ER 🟢 Bile duct obstruction/gallstones, Asteraceae allergy, pregnancy/breastfeeding.
8.3 Individual [stop_items] are formatted as <li></li> 🟢 Each item is an <li>.
8.4 Items are as concise as possible. No trailing explanations, elaborations, rationale, attributions, citations, study details, or content after a dash. 🟢 Concise; no trailing clauses.
8.5 Parenthetical qualifiers from the ER bullet ARE preserved as part of the item, kept concise. 🟢 No qualifiers needed dropping; items preserved cleanly.
8.6 When the ER uses ranking notation inside parens (e.g., “>”) normalize to a plain comma-separated list. 🟢 ER contraindications use no ranking notation; items are plain.
8.7 If no [stop_items] are present the section is left empty N/A stop_items are present.

9. Key Interactions

# Description Result Comments
9.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Derived from the interaction bullets.
9.2 [caution_items] represent the Key Interactions from the ER, excluding any already listed as Contraindications 🟢 Six interactions listed; contraindication populations excluded.
9.3 Individual [caution_items] are formatted as <li></li> 🟢 Each item is an <li>.
9.4 Items are as concise as possible. No trailing explanations, elaborations, rationale, attributions, citations, study details, or content after a dash. 🟢 Concise; severity/consequence text stripped.
9.5 Parenthetical qualifiers from the ER bullet — example drug lists, etc. — ARE preserved, kept concise. 🟢 Example-drug parentheticals preserved (statins, metformin, ACE inhibitors, etc.).
9.6 When the ER uses ranking notation inside parens normalize to a plain comma-separated list. 🟢 No ranking notation in ER interactions; lists are plain.
9.7 If no [caution_items] are present the section is left empty N/A caution_items are present.

10. Protocol

# Description Result Comments
10.1 The section is derived from the ER Protocol section 🟢 Dose/Form/Timing derived from Therapeutic Protocol.
10.2 The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section 🟢 Dose, Form, Timing are the key actionable aspects.
10.3 If less than three distinct actionable aspects are mentioned, unused sets are left empty/invisible. N/A Three distinct aspects are present.
10.4 All used [action_#_label/value/sub] items are filled with meaningful content derived from the ER Protocol section. 🟢 All three cells populated with ER-sourced content.

11. Time to Effect

# Description Result Comments
11.1 The three sets of [time] items cover the three most important time-to-effect aspects from the ER 🟢 Lipids, Digestion, Immediate effect.
11.2 The sets are picked and ordered by the magnitude of the related benefit 🟢 Lipids (highest benefit) first, then digestion.
11.3 If less than three distinct time-to-effect aspects are mentioned, unused sets are left empty/invisible. N/A Three aspects are present.
11.4 All used [time_#_label/value/sub] items are filled with meaningful content derived from the ER. 🟢 All cells populated from Practical Considerations.
11.5 If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel N/A ER provides time-to-effect information.

12. Benefits

# Description Result Comments
12.1 The section is derived from the ER Expected Benefits section 🟢 Tiers mirror the ER Expected Benefits.
12.2 Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] 🟢 All four tiers populated.
12.3 Items are as concise as possible. No explanations, elaborations, effect sizes, qualifiers, attributions, citations, study details, or mechanistic explanations. 🟢 Concise benefit labels only.
12.4 Parenthetical content — including effect sizes, sample notes, mechanistic hints, example studies — is stripped, NOT preserved. 🟢 No parentheticals present.
12.5 If no items of a sub-section are present the respective SPAN is set to display=none. N/A All four tiers have items.

13. Risks

# Description Result Comments
13.1 The section is derived from the ER Potential Risks & Side Effects section 🟢 Tiers mirror the ER risk section.
13.2 Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] 🟢 All four tiers populated.
13.3 Items are as concise as possible. No explanations, elaborations, effect sizes, qualifiers, attributions, citations, study details, or mechanistic explanations. 🟢 Concise risk labels only.
13.4 Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, example studies — is stripped, NOT preserved. 🟢 No parentheticals present.
13.5 If no items of a sub-section are present the respective SPAN is set to display=none. N/A All four tiers have items.

14. Monitoring

# Description Result Comments
14.1 The section is derived from the ER Monitoring section 🟢 Markers, targets, and “why” drawn from the Monitoring table.
14.2 All measurable/quantifiable biomarkers from the Monitoring section are listed 🟢 All 7 (LDL, total cholesterol, triglycerides, HDL, ALT, AST, fasting glucose) present.
14.3 [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. 🟢 Cadence (~8–12 weeks, then every 6–12 months; early BP checks) populated from ER.

15. Qualitative Assessment

# Description Result Comments
15.1 The section is derived from the ER Monitoring section 🟢 Drawn from the ER qualitative markers.
15.2 All subjective/qualitative biomarkers from the Monitoring section are listed 🟢 Digestive comfort, bowel regularity, general energy/tolerability all present.

Issues 22/06/2026 06:11

Pass rate 100.00%. No issues found.