Bronchogen, a lab-made peptide (a short chain of four amino acids) sold as a supplement and research peptide, is promoted for airway resilience with age. Evidence is thin: mostly cell and rat studies, nearly all from its developer, plus one unpublished human report. No harms are documented, reflecting a lack of study rather than demonstrated safety; concerns are product purity, a theoretical growth-promoting signal and delayed evaluation of breathing symptoms. (Full Review)
| Marker | Target | Why |
|---|---|---|
| FEV1/FVC ratio | ≥ 0.75 | Detects airflow obstruction |
| FEV1 (% predicted) | ≥ 90% of predicted | Tracks lung-function change |
| SpO2 at rest | 96–99% | Screens gas exchange |
| hs-CRP | < 1.0 mg/L | General inflammation marker |
| Blood eosinophils | 100–300 cells/µL | Flags allergic-type airway inflammation |
| ALT | < 25 U/L | Liver safety baseline |
| eGFR | > 90 mL/min/1.73 m² | Kidney function baseline |
Cadence: Baseline before a first course; symptoms at 2 and 4 weeks; spirometry and SpO2 after each 30-day course, then every 6–12 months while courses continue; blood tests yearly or after injectable courses