Butea superba to Improve Testosterone - Quick Reference Sheet

Butea superba to Improve Testosterone

Created on 07/23/2026 – Quick Reference based on Evidence Review created using AI4L / Opus 4.8 Audit

A traditional Thai tonic marketed to raise testosterone, but human proof is essentially absent and high animal doses lowered it. The strongest signal is for firmer erections, from one small study clouded by hidden prescription-drug contamination. The main danger is adulteration, which can dangerously lower blood pressure alongside heart medicines. (Full Review)

Protocol

Typical Dose
400–1,000 mg/day
Dried tuber (root) powder; low end preferred
Timing
Morning
Or before activity; convention, not evidence
Trial Length
8–12 weeks
Defined trial, then reassess
Time to effect
Erectile Effect
Weeks
Human trial ran three months
Testosterone
No change
No measurable effect on any timescale

Benefits

Contraindications
  • Nitrates or nitric-oxide donors (nitroglycerin, isosorbide)
  • Significant liver disease
  • Hormone-sensitive cancers (e.g., prostate cancer)
  • Women, especially pregnancy or breastfeeding
Key Interactions
  • PDE5 inhibitors (sildenafil, tadalafil, vardenafil)
  • Antihypertensive drugs (alpha-blockers such as doxazosin)
  • Anticoagulant and antiplatelet drugs (warfarin, aspirin, clopidogrel)
  • Hormone-active supplements (testosterone, DHEA, estrogen-modulating herbs)

Risk & Side Effects

  • High:
  • Medium: Product adulteration with hidden prescription drugs
  • Low: Testosterone suppression at high doses, hepatic and blood-chemistry changes, cardiovascular and blood-pressure effects
  • Speculative: Genotoxicity signal, hormonal disruption from phytoestrogen activity, hyperandrogenemia

Monitoring

Marker Target Why
Total testosterone ~500–900 ng/dL Defines whether a deficit exists and whether the herb changes it
Free testosterone ~15–25 pg/mL (upper half) The bioavailable fraction most tied to symptoms
Luteinizing hormone (LH) ~2–8 IU/L Pituitary signal to make testosterone; helps locate cause of low levels
Follicle-stimulating hormone (FSH) ~1.5–8 IU/L Distinguishes testicular vs. pituitary causes
Sex hormone-binding globulin (SHBG) ~20–40 nmol/L Determines how much testosterone is free vs. bound
Estradiol ~20–30 pg/mL Herb's isoflavones act on estrogen pathways; watch for imbalance
ALT / AST ALT <25 U/L; AST <25 U/L Detects the liver stress flagged in animal studies
Alkaline phosphatase (ALP) ~40–100 U/L Rose at high doses in animals; liver/bone marker
Prostate-specific antigen (PSA) <1.0–1.5 ng/mL Prudent given androgenic marketing and prostate sensitivity
Hematocrit (within CBC) ~40–48% High-dose animal data altered blood counts; androgens can thicken blood

Cadence: Baseline before starting; repeat hormone and liver panels at 6–8 weeks and 12 weeks, then discontinue if no objective benefit

Qualitative Assessment

  • Erection quality and frequency
  • Libido and sexual satisfaction
  • Energy and general vitality
  • Adverse signs: unusual fatigue, abdominal discomfort, dizziness or lightheadedness