A well-tolerated fungal supplement with a modest, uncertain benefit ceiling. The most credible human evidence shows small, inconsistent gains in aerobic capacity, mainly in older or less-trained people, plus signals of immune and kidney support drawn from patients. Energy and healthy-aging claims rest largely on lab and animal work. Best as an add-on to training. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Fasting glucose | 4.4–5.0 mmol/L (79–90 mg/dL) | Detects additive glucose lowering |
| Hemoglobin A1c | < 5.4% | Tracks average blood sugar over months |
| eGFR / serum creatinine | eGFR > 90 mL/min/1.73 m² | Baseline kidney filtration; relevant to kidney-support claims |
| Blood urea nitrogen (BUN) | 10–16 mg/dL | Kidney waste-clearance marker |
| hs-CRP | < 1.0 mg/L | Gauges baseline inflammation and any change |
| ALT / AST | ALT < 25 U/L; AST < 25 U/L | Screens for liver stress during use |
| Platelet count / coagulation | Platelets 150–400 ×10⁹/L; INR in target if on warfarin | Watches additive bleeding risk |
Cadence: Recheck at 8–12 weeks after starting, then every 6–12 months (more often if using diabetes or anticoagulant medication)