Dehydrozingerone is a ginger-derived compound, half of curcumin, that dissolves in water far better. Lab and animal work suggests it neutralizes cell-damaging molecules, calms inflammation, and helps the body handle blood sugar, with early hints for brain and mood. But no human studies of any kind exist — no safety, no dosing. Best viewed today as a research compound. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Fasting glucose | 70–85 mg/dL | Tracks the proposed glucose-lowering effect |
| HbA1c | < 5.4% | Captures sustained glycemic effect |
| Fasting insulin | 2–5 µIU/mL | Reflects insulin-sensitizing (AMPK) rationale |
| hs-CRP | < 1.0 mg/L | Monitors the anti-inflammatory rationale |
| ALT/AST | ALT < 25 U/L (M), < 22 U/L (F) | Surveillance for any hepatic effect of an uncharacterized compound |
| eGFR / creatinine | eGFR > 90 mL/min/1.73m² | Kidney is the main distribution/excretion site |
Cadence: Baseline, at roughly 8–12 weeks, then every 6–12 months