Audit: QRS - Eucommia Bark for Health & Longevity

Audit conducted on 16/08/2026 14:50 using AI4L / Opus 5

Iterations

Summary

Items Count
Total 93
Passed 85
Failed 0
N/A 8
Pass Rate 100.00%
  • Total = Passed + Failed + N/A
  • Pass Rate = Passed / (Passed + Failed) × 100
  • N/A items are excluded from the pass rate calculation

1. General Rules

# Description Result Comments
1.1 Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. 🟢 Every populated variable traces to ER text: protocol cells to ER lines 353/355/361, time cells to ER 406 and 180, benefits to ER 156–222, risks to ER 250–288, gates to ER 308–331, monitoring table and cadence to ER 436–448, qualitative items to ER 452–456.
1.2 Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. 🟢 Hedges carried through: “theoretical bruising or bleeding”, “possible additive glucose lowering”, “no outcome figure in people”, “never measured in people”.
1.3 The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). 🟢 Contraindications remain absolute; the blood-pressure claim stays bounded to “only at the higher dose”; the rodent basis of the renal and adiposity signals is retained.
1.4 The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. 🟢 Gates come only from ER Key Interactions & Contraindications; benefits only from Expected Benefits; risks only from Potential Risks & Side Effects; no Benefit- or Risk-Modifying Factor is surfaced anywhere.
1.5 PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. 🟢 The rendered sheet carries no PMID, citation, NCT identifier, author name, or brand.
1.6 The QRS does not introduce new attributions. 🟢 No attribution appears beyond the template’s own AI4L link.

2. Focus, Tone & Audience

# Description Result Comments
2.1 The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. 🟢 Measured, sceptical, precise — mirrors the ER’s own register throughout.
2.2 The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging 🟢 Objective and data-driven throughout, with an actionable handle (“Inexpensive and easy to monitor, plausibly useful just above optimal pressure”).
2.3 The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor 🟢 Descriptive throughout; no imperatives or prescriptions.
2.4 The QRS avoids language that implies medical or clinical advice 🟢 Monitoring “Why” cells state what a marker detects, not what to do about it.
2.5 The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” 🟢 No instance of “recommend”, “advise”, or “should” in the document body.
2.6 The QRS never addresses “the reader” directly — it presents evidence, not guidance 🟢 No second-person pronoun appears anywhere in the document.
2.7 The QRS is written in plain language, avoiding unnecessary medical jargon 🟢 Technical terms appear only where they are the ER’s own biomarker names; drug classes carry the ER’s plain-language glosses.
2.8 Information is presented in a concise and very compact manner 🟢 Gate and tier items are reduced to key facts; sub-lines run one to two clauses.
2.9 It DOES NOT address the reader directly 🟢 Confirmed — no direct address in any variable.
2.10 The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. 🟢 Optimal-range monitoring targets (eGFR above 90, hs-CRP under 1.0, HbA1c 4.8–5.4%) rather than conventional disease cut-offs.
2.11 The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. 🟢 Nine-marker panel, daily home pressure logging, and a three-times-daily dosing schedule are presented without simplification.
2.12 The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. 🟢 No general-population framing, no simplified “ask your doctor” register.
2.13 Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. 🟢 The at-a-glance flags the narrow band just above optimal pressure — the audience-specific signal — rather than a hypertension-treatment framing.
2.14 The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” (e.g., “American Academy of Anti-Aging Medicine”) are quoted verbatim. 🟢 “anti-aging” does not appear; the title uses “Health & Longevity”.
2.15 The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. 🟢 Formal register throughout; the only plain-language glosses (“blood thinners”, “drugs that increase urine output”) are the ER’s own verbatim bold labels.

3. Template Integrity

# Description Result Comments
3.1 The following labels and headings on the QRS are fixed and not modified:
• Card and section headings: “Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”
• Gate headings: “Contraindications”, “Key Interactions”
• Tier labels: “High”, “Medium”, “Low”, “Speculative”
• Table column headers in Monitoring: “Marker”, “Target”, “Why”
🟢 All headings match the template byte-for-byte (lines 445, 491, 539, 565, 584, 629, 652, 656–658, 788); visible tier labels “Medium”, “Low”, “Speculative” are unchanged.
3.2 All “” from the [qrs_template] are present in the the QRS. 🟢 All 37 template variable names are present, with the indexed families expanded to marker_1–9 and qualitative_item_1–5.
3.3 Spans that are not addressed in a checklist item are left unchanged 🟢 The non-variable spans (website="evidence_review", website="audit", website="full_review"), the stylesheet link, footer disclaimer, and all CSS are byte-identical to the template.

4. Formatting

# Description Result Comments
4.1 When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” N/A No source ER section is empty; the absent High tiers are governed by items 12.5 and 13.5 instead.
4.2 Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. 🟢 All three protocol labels and all eight interaction labels reproduce the ER bold labels verbatim, including their parenthetical glosses.
4.3 Labels are not paraphrased, abbreviated, or invented. 🟢 Monitoring row labels are verbatim ER table names; time-panel cell labels take the ER’s own wording (“Blood pressure”, “Bone endpoints”, ER line 406).
4.4 The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. 🟢 No emoji present; the ER’s “⚠️ Conflicted” markers were correctly dropped.
4.5 The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. 🟢 Interaction drug lists were trimmed to three or four examples and gate items stripped of rationale to hold the one-page budget.

5. Metadata

# Description Result Comments
5.1 The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. 🟢 Lines 2–14, immediately after the doctype and before the template comment on line 16.
5.2 Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. 🟢 Opening “—” on line 3, closing “—” on line 13; the preamble text sits on line 2.
5.3 The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. 🟢 Enclosed in an HTML comment and not duplicated anywhere in head or body.
5.4 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Only duration: "00:04" is quoted, which its colon requires.
5.5 The filename of the source ER is stated as “er_filename: [er_filename]” 🟢 Line 4: er_filename: eucommia_bark_2026-0825-1213_Opus_ER.md, matching the ER frontmatter.
5.6 Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” 🟢 Line 5: qrs_prompt_version: 26.7.02, matching the QRS.md badge.
5.7 Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” (e.g., 2026-0501-1430) 🟢 Line 6: qrs_creation_date: 2026-0816-1440, correct format.
5.8 The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” 🟢 Line 7: qrs_creator_ai_nickname: Opus.
5.9 The nickname of the AI is just a single word model name without version, etc. (e.g., Opus, Sonnet, Grok, Gemini, ChatGPT) 🟢 “Opus” — single word, no version or qualifier.
5.10 The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” 🟢 Line 8: qrs_creator_ai_fullname: Opus 5.
5.11 The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier (e.g., Opus 4.6, Sonnet 3.2, Grok 4.5, Gemini 3.1, ChatGPT 5.4) 🟢 “Opus 5” — nickname plus version, no context-window or other qualifier.
5.12 The filename of the document is stated as “qrs_filename: [filename of this document]” 🟢 Line 9 matches the actual file on disk.
5.13 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Re-verified across all nine keys; no stray whitespace or unnecessary quoting.

6. Page Title & Header

# Description Result Comments
6.1 [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet” (e.g., “Intervention - Quick Reference Sheet”). The [canonical_topic] is HTML-entity-encoded as needed (e.g., &amp; for &) 🟢 Line 22: “Eucommia Bark for Health & Longevity - Quick Reference Sheet”, matching ER canonical_topic with the ampersand encoded.
6.2 [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed (e.g., &amp; for &) 🟢 Line 417: “Eucommia Bark for Health & Longevity”.
6.3 [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] 🟢 Line 421: “08/16/2026”, the correct rendering of 2026-0816-1440.
6.4 [header_subline_model] is set to [qrs_creator_ai_fullname] 🟢 Line 425: “Opus 5”, matching the frontmatter value.
6.5 No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. 🟢 Header block (lines 415–428) is structurally identical to the template; no alternate-names line despite the ER carrying seven.

7. At-A-Glance Section

# Description Result Comments
7.1 [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section 🟢 Compresses ER lines 480–484, closing on the decision-relevant handle (cheap, monitorable, narrow band above optimal pressure).
7.2 [at_a_glance] is no longer than 60 words 🟢 56 words.
7.3 Every fact in [at_a_glance] is supported by a distinct passage in the ER. 🟢 Each clause maps to the Conclusion: chemistry/human record (line 480), animal actions (480), the dose-split trial (480), cost and monitorability (484), renal and oestrogen uncertainty (482).
7.4 It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead 🟢 No acronym appears; “vessel relaxation”, “bone-cell effects”, and “gut bacterial shifts” replace the ER’s mechanistic vocabulary.
7.5 It DOES NOT cite specific trials (names, years, sample sizes, p-values) 🟢 “one short controlled trial” carries no name, year, or sample size.
7.6 It DOES NOT cite effect sizes, relative risks, or statistical results 🟢 The −7.5/−3.9 mmHg figure and the pooled SMD are both absent.

8. Contraindications

# Description Result Comments
8.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 All six items map to the ER’s “Populations who should avoid Eucommia Bark” list, ER lines 326–331.
8.2 [stop_items] represent the Contraindications from the ER 🟢 All six ER avoid-populations are present, none added.
8.3 Individual [stop_items] are formatted as <li></li> 🟢 Six <li> elements inside the span, lines 568–579.
8.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 The ER’s trailing rationales (“no human safety data exist despite traditional use”, “given the theoretical bleeding and blood-pressure effects”) are stripped; no dash-trailing clause remains.
8.5 Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 “stage 3b or worse”, “under 45 mL/min/1.73 m²”, “below 100 mmHg”, “within two weeks”, and the aromatase-inhibitor/tamoxifen list are all retained.
8.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. N/A The ER uses no ranking notation in this section.
8.7 The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no population, condition, or scenario for which the intervention should be avoided, deferred, or used only under specialist supervision. 🟢 The ER names six such populations and the section is correspondingly populated.
8.8 If the section is left empty, an HTML comment inside the [stop_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. N/A The section is not empty.

9. Key Interactions

# Description Result Comments
9.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 All eight items map one-to-one onto ER lines 308–322.
9.2 [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications 🟢 All eight ER interaction bullets are present; none duplicates a contraindication.
9.3 Individual [caution_items] are formatted as <li></li> 🟢 Eight <li> elements inside the span, lines 587–619.
9.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 The ER’s “Mitigation is …” sentences are all stripped; each item reduces to the consequence plus example drugs.
9.5 Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 Every bullet retains a named example list, trimmed to three to five agents for the page budget; none is dropped entirely.
9.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. N/A The ER uses no ranking notation in this section.
9.7 The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no interaction, additive effect, or exposure that changes how the intervention is used. 🟢 The ER names eight interaction classes and the section is correspondingly populated.
9.8 If the section is left empty, an HTML comment inside the [caution_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. N/A The section is not empty.

10. Protocol

# Description Result Comments
10.1 The section is derived from the ER Protocol section 🟢 All three cells come from the ER Therapeutic Protocol bullets at lines 353, 355, and 361.
10.2 The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section 🟢 The two competing dosing routes (which the ER frames as “neither default”) plus timing — the only bullets that state what to take, how much, and when.
10.3 If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. N/A The ER Therapeutic Protocol section carries eleven actionable bullets, well above three.
10.4 All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. 🟢 All nine cells populated; labels verbatim, values (“1 g, three times daily”, “6–15 g dried bark daily”, “Divided, with meals”) and subs all traceable to the ER bullets.

11. Time to Effect

# Description Result Comments
11.1 The three sets of [time] items cover the three most important time-to-effect aspects from the ER 🟢 Blood pressure and bone from the ER “Time to effect” bullet (line 406); adiposity and lipids from the ER magnitude statement at line 180.
11.2 The sets are picked and ordered by the magnitude of the related benefit 🟢 Blood pressure (Medium tier) first, then the two Low-tier benefits in the ER’s own order — bone before adiposity.
11.3 If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. N/A Three distinct time-to-effect aspects are present in the ER.
11.4 All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. 🟢 All nine cells populated; “2 weeks”, “6–12 months”, and “4 weeks or longer” each match the ER figures, and each sub retains the ER’s evidentiary caveat.
11.5 If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel N/A The ER does provide time-to-effect information, so the section is correctly retained.

12. Benefits

# Description Result Comments
12.1 The section is derived from the ER Expected Benefits section 🟢 All thirteen entries correspond to ER benefit headings at lines 156–222.
12.2 Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] 🟢 All four spans present at lines 541, 542, 545, 552.
12.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Bare benefit names only; the ER’s magnitude blocks, the −7.5/−3.9 mmHg figure, and the pooled SMD are all omitted.
12.4 Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 No parenthetical content appears in any benefit tier.
12.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. 🟢 The ER states no benefit reaches High; benefits_high is set to style="display: none" with no empty-state text (line 541).

13. Risks

# Description Result Comments
13.1 The section is derived from the ER Potential Risks & Side Effects section 🟢 All seven entries correspond to ER risk headings at lines 250–288.
13.2 Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] 🟢 All four spans present at lines 631, 632, 635, 641.
13.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Bare risk names only; the rodent dosing figures and the 13-week study details are omitted.
13.4 Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 No parenthetical content appears in any risk tier.
13.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. 🟢 The ER states no risk reaches High; risks_high is set to style="display: none" with no empty-state text (line 631).

14. Monitoring

# Description Result Comments
14.1 The section is derived from the ER Monitoring section 🟢 Table rows and cadence come from the ER Monitoring Protocol & Defining Success section, lines 436–448.
14.2 All measurable/quantifiable biomarkers from the Monitoring section are listed 🟢 All nine ER table rows are present, with marker names, optimal ranges, and “Why Measure It?” text reproduced verbatim.
14.3 [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. 🟢 Line 778 reproduces the ER cadence sentence from line 436 in full.

15. Qualitative Assessment

# Description Result Comments
15.1 The section is derived from the ER Monitoring section 🟢 Drawn from the ER’s “Qualitative markers worth tracking alongside the labs” list, lines 452–456.
15.2 All subjective/qualitative biomarkers from the Monitoring section are listed 🟢 All five ER qualitative markers are present and verbatim; none added or dropped.

Issues 16/08/2026 14:50

Pass rate 100.00%. No issues found.

Issues 16/08/2026 14:46

  1. 4.5 — Decision gates exceed page budget: [caution_items] (lines 589–624) carries the ER’s full example lists and mechanistic phrasing untrimmed — the seven-item supplement list at lines 612–614, the five-item bleeding-risk list at 617–618, and “volume depletion raises” at 595 — running roughly 26 rendered lines and pushing the gate block alone to about half the A4 print area, where 9.5 permits these lists to be shortened to fit.
  2. 2.15 — “test” instead of “trial”: [at_a_glance] line 435 reads “one short human test” where the ER Conclusion (line 480) says “One short controlled trial”; the QRS uses the formal term “trial” at lines 504 and 675, so the register is inconsistent.

Fixes 16/08/2026 14:46

  1. 4.5 — Decision-gate lists trimmed to page budget: Shortened the [caution_items] example lists (supplements from seven to five, bleeding-risk from five to three, anticoagulants from five to three, antihypertensives from four to three, other interventions from five to four) and dropped the mechanistic phrases “volume depletion” and “added”; also condensed two [stop_items] entries, cutting the gate block by roughly seven rendered lines.
  2. 2.15 — “test” replaced with “controlled trial”: Changed [at_a_glance] “one short human test lowered blood pressure” to “one short controlled trial lowered blood pressure”, matching the ER Conclusion wording and the formal register used elsewhere in the sheet.