Iberin is a reactive sulfur compound released when cabbage-family vegetables are cut or chewed. Like its close relative sulforaphane, it switches on the cell's own protective and waste-clearing programs. What is known comes almost entirely from cells in culture and a handful of animal experiments. Nothing has been tested against a health outcome in a person. (Full Review)
| Marker | Target | Why |
|---|---|---|
| TSH | 0.5-2.0 mIU/L | Detects the thyroid suppression that is the main theoretical hazard |
| Free T4 | 1.0-1.5 ng/dL | Confirms actual hormone output when TSH shifts |
| TPO antibodies | Negative, below 9 IU/mL | Identifies pre-existing autoimmune thyroid disease before loading begins |
| hs-CRP | Below 0.5 mg/L | Tracks the systemic inflammation the intervention is proposed to lower |
| GGT | Below 20 U/L | Proxy for glutathione turnover, which iberin consumes and induces |
| ALT | Below 20 U/L in men, below 17 U/L in women | Detects liver-cell stress from any concentrated extract |
| eGFR | Above 90 mL/min/1.73 m² | Clearance of iberin conjugates depends on renal tubular secretion |
| Urinary isothiocyanate conjugates | No established target exists; track the change from the individual's own pre-intervention baseline | Verifies that dietary intake is actually producing systemic exposure |
Cadence: Baseline panel before starting a sustained high-cruciferous protocol; thyroid panel repeated at 12 weeks, then at 6 and 12 months; inflammatory, liver and kidney markers every 6 to 12 months thereafter. TPO antibodies once at baseline unless the thyroid panel shifts.