Inositol is an inexpensive, well-tolerated compound acting as a messenger for insulin and several hormones. Strongest evidence supports better insulin response and more regular cycles and ovulation in a common hormonal condition, comparable to a standard medication with fewer digestive complaints. Blood-sugar prevention in pregnancy, egg quality, sleep, and mood remain unconfirmed. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Fasting insulin | 2–5 µIU/mL | Most sensitive early marker of insulin resistance |
| Fasting glucose | 75–85 mg/dL | Tracks blood-sugar control |
| HOMA-IR | < 1.0 | Primary insulin-resistance response marker |
| HbA1c | < 5.3% | Average blood sugar over ~3 months |
| Total & free testosterone | Total 15–45 ng/dL (women) | Tracks androgen excess in polycystic ovary syndrome |
| Sex hormone-binding globulin | 40–80 nmol/L (women) | Rises as insulin falls, lowering active androgens |
| Triglycerides | < 80 mg/dL | Metabolic-syndrome marker responsive to insulin sensitization |
| HDL cholesterol | > 60 mg/dL | Protective lipid marker that can improve with metabolic gains |
Cadence: Baseline, at 12 weeks after starting, then every 6–12 months