Audit: QRS - Kava for Health & Longevity
Audit conducted on 16/08/2026 23:05 using AI4L / Opus 5
Summary
| Items | Count |
|---|---|
| Total | 93 |
| Passed | 83 |
| Failed | 0 |
| N/A | 10 |
| Pass Rate | 100.00% |
- Total = Passed + Failed + N/A
- Pass Rate = Passed / (Passed + Failed) × 100
- N/A items are excluded from the pass rate calculation
1. General Rules
| # | Description | Result | Comments |
|---|---|---|---|
| 1.1 | Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. | 🟢 | Every populated span traces to ER text: protocol cells to ER Therapeutic Protocol (lines 371, 373, 381, 385, 391), time cells to line 430 and 458, benefit/risk tiers to the ER Expected Benefits and Potential Risks & Side Effects headings, gates to Key Interactions & Contraindications (lines 312–343), monitoring to the table at lines 462–470, qualitative items to lines 474–479. |
| 1.2 | Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. | 🟢 | The ER’s “⚠️ Conflicted” markers are carried through as “(conflicted)” on all four affected items (benefits_high, benefits_low, risks_high, risks_low); “theoretical infection risk” is preserved verbatim in marker_7_why. |
| 1.3 | The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). | 🟢 | Absolute contraindications from the ER (dopaminergic drugs, benzodiazepines, surgery window) remain in the Contraindications gate rather than being demoted to Key Interactions; no cautionary item is upgraded to a prohibition. |
| 1.4 | The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. | 🟢 | Nothing from Benefit-Modifying Factors (lines 203–217) or Risk-Modifying Factors (lines 293–307) appears in the gates or the risk tiers; gates draw exclusively on Key Interactions & Contraindications. |
| 1.5 | PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. | 🟢 | The QRS contains no PMIDs, citations, author names, NCT identifiers, or brand names at all. |
| 1.6 | The QRS does not introduce new attributions. | 🟢 | No attributions of any kind appear in the QRS. |
2. Focus, Tone & Audience
| # | Description | Result | Comments |
|---|---|---|---|
| 2.1 | The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. | 🟢 | The measured, disagreement-acknowledging register of the ER Conclusion is mirrored in at_a_glance (“a real but uneven record”, “signals are thinner”). |
| 2.2 | The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging | 🟢 | Monitoring targets and dosing values give the data-driven spine; “Deliberate short use with liver testing changes the picture” supplies the empowering framing without overclaiming. |
| 2.3 | The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor | 🟢 | Content is stated as facts and ranges, not as instructions issued to a patient. |
| 2.4 | The QRS avoids language that implies medical or clinical advice | 🟢 | No imperative clinical directives; the gates name populations and agents rather than telling anyone what to do. |
| 2.5 | The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” | 🟢 | No instances of “recommend”, “advise”, or “should” directed at a reader. |
| 2.6 | The QRS never addresses “the reader” directly — it presents evidence, not guidance | 🟢 | No second-person pronouns anywhere in the document. |
| 2.7 | The QRS is written in plain language, avoiding unnecessary medical jargon | 🟢 | Technical terms that remain (CYP2E1 substrates, Child-Pugh, cholestatic) are load-bearing decision content and are carried from the ER with its own glosses where the ER supplied them (“cholestatic (bile-flow blockage)”). |
| 2.8 | Information is presented in a concise and very compact manner | 🟢 | Every tier is a single semicolon-separated line; gate items are noun phrases with no trailing rationale. |
| 2.9 | It DOES NOT address the reader directly | 🟢 | Confirmed by scan: no “you”, “your”, or “yours”. |
| 2.10 | The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. | 🟢 | The sheet assumes a reader who will order a fasted liver panel, log nightly sleep, and track an anxiety score. |
| 2.11 | The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. | 🟢 | The monitoring cadence (baseline, week 4, week 8, then every 8 weeks, plus unscheduled draws) presumes exactly that willingness. |
| 2.12 | The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. | 🟢 | Functional-range targets tighter than conventional laboratory ranges and a nine-marker panel are not general-population content. |
| 2.13 | Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. | 🟢 | at_a_glance closes on precisely that distinction — “Deliberate short use with liver testing changes the picture” — mirroring the ER Conclusion line 507. |
| 2.14 | The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” (e.g., “American Academy of Anti-Aging Medicine”) are quoted verbatim. | 🟢 | The string “anti-aging” does not occur; the title uses “Health & Longevity”. |
| 2.15 | The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. | 🟢 | “alanine aminotransferase”, “central nervous system depression”, “psychomotor effects”, “dermopathy” are used rather than consumer equivalents; the plainer wording in at_a_glance is required there by item 7.4. |
3. Template Integrity
| # | Description | Result | Comments |
|---|---|---|---|
| 3.1 | The following labels and headings on the QRS are fixed and not modified: Card and section headings: “Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”; Gate headings: “Contraindications”, “Key Interactions”; Tier labels: “High”, “Medium”, “Low”, “Speculative”; Table column headers in Monitoring: “Marker”, “Target”, “Why” | 🟢 | All fourteen fixed strings match the template byte for byte (lines 440, 477, 519, 539, 557, 576, 595, 599–601, 714). |
| 3.2 | All “…” from the [qrs_template] are present in the the QRS. | 🟢 | Full span-name comparison against the template: all 38 template names present, with marker_#_* expanded to markers 1–9 and qualitative_item_# expanded to items 1–6. |
| 3.3 | Spans that are not addressed in a checklist item are left unchanged | 🟢 | A line-level diff against the template shows changes confined to the metadata block, page_title, and the checklist-addressed content spans; <span website="evidence_review">, <span website="audit">, and <span website="full_review"> are untouched, as are all CSS and structural markup. |
4. Formatting
| # | Description | Result | Comments |
|---|---|---|---|
| 4.1 | When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” | N/A | No ER section feeding the QRS is empty — every benefit and risk tier, both gate lists, the protocol, the monitoring table and the qualitative list are populated in the ER. |
| 4.2 | Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. | 🟢 | action_1_label “Standard extract protocol”, action_2_label “Traditional aqueous protocol” and action_3_label “Single versus split dosing” reproduce the ER bold labels at lines 371, 373 and 385 exactly. |
| 4.3 | Labels are not paraphrased, abbreviated, or invented. | 🟢 | Marker names match the ER biomarker column verbatim, tier contents match the ER headings, and the protocol labels match the ER bold labels. |
| 4.4 | The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. | 🟢 | Scan for emoji code points returns nothing; the ER’s tier emoji and “⚠️” markers are rendered as CSS colour plus the bold “High/Medium/Low/Speculative” labels and the word “(conflicted)”. |
| 4.5 | The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. | 🟢 | Every section is condensed to headings or noun phrases rather than carried over at ER length; no section is spilled into additional structure and no extra page container exists. |
5. Metadata
| # | Description | Result | Comments |
|---|---|---|---|
| 5.1 | The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. | 🟢 | The comment opens at line 2, immediately after <!doctype html> at line 1, and closes at line 14 before any other markup. |
| 5.2 | Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. | 🟢 | Opening --- at line 3, closing --- at line 13; the preamble text “QRS — Metadata (invisible, parsed by audit tooling)” sits before the opening delimiter. |
| 5.3 | The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. | 🟢 | It is inside an HTML comment and none of its values are repeated in any rendered element. |
| 5.4 | All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. | 🟢 | Only duration: "00:04" is quoted, and it contains a colon, so quoting is required; all other values are bare and untrimmed of nothing. |
| 5.5 | The filename of the source ER is stated as “er_filename: [er_filename]” | 🟢 | Line 4: er_filename: kava_2026-0825-1918_Opus_ER.md, which is the ER under audit. |
| 5.6 | Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” | 🟢 | Line 5: qrs_prompt_version: 26.7.02, matching the version badge of QRS.md. |
| 5.7 | Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” (e.g., 2026-0501-1430) | 🟢 | Line 6: qrs_creation_date: 2026-0816-2252, in the required format. |
| 5.8 | The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” | 🟢 | Line 7: qrs_creator_ai_nickname: Opus. |
| 5.9 | The nickname of the AI is just a single word model name without version, etc. (e.g., Opus, Sonnet, Grok, Gemini, ChatGPT) | 🟢 | “Opus” is a single word with no version or qualifier. |
| 5.10 | The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” | 🟢 | Line 8: qrs_creator_ai_fullname: Opus 5. |
| 5.11 | The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier (e.g., Opus 4.6, Sonnet 3.2, Grok 4.5, Gemini 3.1, ChatGPT 5.4) | 🟢 | “Opus 5” is nickname plus version number with no trailing qualifier. |
| 5.12 | The filename of the document is stated as “qrs_filename: [filename of this document]” | 🟢 | Line 9: qrs_filename: kava_2026-0825-1918_Opus_QRS.html, matching the file on disk. |
| 5.13 | All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. | 🟢 | Re-verified across all nine keys; only the colon-bearing duration carries quotes. |
6. Page Title & Header
| # | Description | Result | Comments |
|---|---|---|---|
| 6.1 | [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet” (e.g., “Intervention - Quick Reference Sheet”). The [canonical_topic] is HTML-entity-encoded as needed (e.g., & for &) |
🟢 | Line 22: Kava for Health & Longevity - Quick Reference Sheet, matching ER canonical_topic with the ampersand encoded. |
| 6.2 | [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed (e.g., & for &) |
🟢 | Line 417: Kava for Health & Longevity. |
| 6.3 | [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] | 🟢 | Line 421: 08/16/2026, the correct reformatting of 2026-0816-2252. |
| 6.4 | [header_subline_model] is set to [qrs_creator_ai_fullname] | 🟢 | Line 425: Opus 5, matching the frontmatter value. |
| 6.5 | No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. | 🟢 | The header holds only the title and the template subline; the ER’s “Also known as” list (line 31) is correctly absent. |
7. At-A-Glance Section
| # | Description | Result | Comments |
|---|---|---|---|
| 7.1 | [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section |
🟢 | All four sentences map onto the ER Conclusion (lines 505–507), ending on the execution-relevant distinction between deliberate monitored use and population averages. |
| 7.2 | [at_a_glance] is no longer than 60 words | 🟢 | 53 words. |
| 7.3 | Every fact in [at_a_glance] is supported by a distinct passage in the ER. | 🟢 | “real but uneven record” and “does not appear to dull attention or memory” from line 505; “Signals for sleep, for low mood … are thinner” from line 505; “the plant part and the solvent used clearly matter” and “pairing kava with alcohol, sedatives” from line 507; “uses kava deliberately and briefly” from line 507. |
| 7.4 | It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead | 🟢 | No acronyms; “root drink”, “brief calming”, “liver testing”, “plant part”, “extraction method” are all everyday terms a non-specialist would use unprompted. |
| 7.5 | It DOES NOT cite specific trials (names, years, sample sizes, p-values) | 🟢 | No trial names, years, sample sizes or p-values appear. |
| 7.6 | It DOES NOT cite effect sizes, relative risks, or statistical results | 🟢 | No numbers of any kind appear in the paragraph. |
8. Contraindications
| # | Description | Result | Comments |
|---|---|---|---|
| 8.1 | The section is derived from the ER Key Interactions & Contraindications section |
🟢 | All eleven items trace to that section: ten to the “Populations who should avoid Kava” list (lines 334–343) and one to the “Dopaminergic drugs” bullet marked “Absolute contraindication” (line 322). |
| 8.2 | [stop_items] represent the Contraindications from the ER | 🟢 | Every ER population bullet is represented, and the ER’s three “Absolute contraindication” interaction bullets are covered — benzodiazepines and surgery via the population bullets, dopaminergic drugs as its own item. |
| 8.3 | Individual [stop_items] are formatted as <li></li> | 🟢 | Lines 542–552: eleven discrete <li> elements inside the stop_items span. |
| 8.4 | Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. | 🟢 | No dashes introduce trailing clauses; the ER’s trailing explanations are stripped, e.g. “the contraindication carried on the former German product label” (line 343) and “(a severity grade for cirrhosis)” (line 334). |
| 8.5 | Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). | 🟢 | “Child-Pugh A–C”, “above twice the upper limit of normal”, “above 14 standard drinks weekly”, “within 14 days”, “under 18” and the levodopa/pramipexole/ropinirole drug list are all retained. |
| 8.6 | When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. | N/A | The ER’s Key Interactions & Contraindications section uses no ranking notation inside parentheses; its parentheticals are plain drug lists. |
| 8.7 | The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no population, condition, or scenario for which the intervention should be avoided, deferred, or used only under specialist supervision. |
🟢 | The section is populated, and the ER does identify such populations, so the emptiness condition is correctly not exercised. |
| 8.8 | If the section is left empty, an HTML comment inside the [stop_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. | N/A | The section is not empty. |
9. Key Interactions
| # | Description | Result | Comments |
|---|---|---|---|
| 9.1 | The section is derived from the ER Key Interactions & Contraindications section |
🟢 | All seven items come from the bullet list at lines 314–328. |
| 9.2 | [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications | 🟢 | The ER’s seven non-absolute interaction bullets are all present; the three absolute-contraindication bullets (benzodiazepines, dopaminergic drugs, surgery and anesthesia) are correctly excluded and appear in the Contraindications gate instead. |
| 9.3 | Individual [caution_items] are formatted as <li></li> | 🟢 | Lines 560–566: seven discrete <li> elements inside the caution_items span. |
| 9.4 | Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. | 🟢 | Each item is reduced to the ER’s bold label plus its drug list; the mechanistic and mitigation sentences (“Additive sedation, respiratory depression risk…”, “Monthly liver-enzyme monitoring applies…”) are stripped. |
| 9.5 | Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). | 🟢 | All six ER example-drug lists are carried through in full and verbatim, including the seven-agent sedative-supplement list. |
| 9.6 | When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. | N/A | The ER uses no ranking notation inside parentheses in this section. |
| 9.7 | The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no interaction, additive effect, or exposure that changes how the intervention is used. |
🟢 | The section is populated, and the ER identifies numerous such interactions, so the emptiness condition is correctly not exercised. |
| 9.8 | If the section is left empty, an HTML comment inside the [caution_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. | N/A | The section is not empty. |
10. Protocol
| # | Description | Result | Comments |
|---|---|---|---|
| 10.1 | The section is derived from the ER Protocol section |
🟢 | All three cells derive from the ER Therapeutic Protocol bullets at lines 371, 373, 381, 385 and 391. |
| 10.2 | The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section |
🟢 | The two dose regimens the ER names as the evidenced starting points, plus the dosing schedule, are the three execution-critical bullets; the competing-approach and unvalidated-genetics bullets are correctly omitted. |
| 10.3 | If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. | N/A | The ER supplies more than three actionable implementation aspects and all three sets are used. |
| 10.4 | All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. |
🟢 | All nine cells carry substantive ER-derived content; the age adjustment in action_1_sub matches line 391 and the timing detail in action_3_sub matches line 381. |
11. Time to Effect
| # | Description | Result | Comments |
|---|---|---|---|
| 11.1 | The three sets of [time] items cover the three most important time-to-effect aspects from the ER | 🟢 | Acute onset, the interval over which rating-scale separation emerged, and the minimum course length before judging — the three distinct horizons stated at ER lines 430 and 458. |
| 11.2 | The sets are picked and ordered by the magnitude of the related benefit | 🟢 | Cells 1 and 2 both attach to the High-tier benefit (short-term anxiety reduction), ordered from acute to cumulative; cell 3 attaches to the combined anxiety and Low-tier sleep endpoints. |
| 11.3 | If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. | N/A | The ER provides three or more distinct time-to-effect aspects and all three sets are used. |
| 11.4 | All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. | 🟢 | “60 to 90 minutes”, “Week 1 to week 4” and “At least 4 weeks” all come from ER line 430; the third sub-cell restates the week-4 review point of line 458. |
| 11.5 | If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel |
N/A | The ER provides explicit time-to-effect information at line 430, so the section is correctly retained. |
12. Benefits
| # | Description | Result | Comments |
|---|---|---|---|
| 12.1 | The section is derived from the ER Expected Benefits section |
🟢 | All seven listed benefits correspond one-to-one with the ER’s seven Expected Benefits sub-headings (lines 156–198). |
| 12.2 | Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] | 🟢 | All four spans are present and populated at lines 521–532, each on its own tier. |
| 12.3 | Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. | 🟢 | Each entry is the ER sub-heading alone; no Magnitude figures (9.69 points, 1.26-fold, p-values) or narrative text is carried across. |
| 12.4 | Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. | 🟢 | No ER parenthetical survives; the only parentheses used are “(conflicted)”, the emoji-free rendering of the ER’s own “⚠️ Conflicted” heading marker required by items 1.2 and 4.4. |
| 12.5 | If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. | N/A | All four ER benefit tiers contain items, so no span needs hiding. |
13. Risks
| # | Description | Result | Comments |
|---|---|---|---|
| 13.1 | The section is derived from the ER Potential Risks & Side Effects section |
🟢 | All ten listed risks correspond one-to-one with the ER’s ten Potential Risks & Side Effects sub-headings (lines 226–288). |
| 13.2 | Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] | 🟢 | All four spans are present and populated at lines 578–589. |
| 13.3 | Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. | 🟢 | Each entry is the ER sub-heading alone; the Magnitude blocks (14 documented cases, p-values, relative risk 2.50) are entirely absent. |
| 13.4 | Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. | 🟢 | No ER parenthetical survives; the only parentheses used are “(conflicted)”, the emoji-free rendering of the ER’s own “⚠️ Conflicted” heading marker required by items 1.2 and 4.4. |
| 13.5 | If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. | N/A | All four ER risk tiers contain items, so no span needs hiding. |
14. Monitoring
| # | Description | Result | Comments |
|---|---|---|---|
| 14.1 | The section is derived from the ER Monitoring section |
🟢 | The table and cadence derive from the ER Monitoring Protocol & Defining Success section (lines 458–470). |
| 14.2 | All measurable/quantifiable biomarkers from the Monitoring section are listed |
🟢 | All nine ER table rows are present with matching names and functional ranges: alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, total bilirubin, albumin, lymphocyte count, anxiety rating score, resting heart rate. |
| 14.3 | [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. |
🟢 | Line 708 reproduces the full cadence of ER line 458: fasted baseline draw, week 4, week 8 or end of course, every 8 weeks thereafter, unscheduled draw on symptoms, plus anxiety and sleep scores at week 4. |
15. Qualitative Assessment
| # | Description | Result | Comments |
|---|---|---|---|
| 15.1 | The section is derived from the ER Monitoring section |
🟢 | All six items come from the “Qualitative markers worth tracking alongside the laboratory panel” list at ER lines 474–479. |
| 15.2 | All subjective/qualitative biomarkers from the Monitoring section are listed |
🟢 | All six ER qualitative markers are present in order: sleep onset and awakenings, daytime alertness, morning grogginess, skin condition, appetite and weight, and subjective ease in previously provoking situations. |
Issues 16/08/2026 23:05
Pass rate 100.00%. No issues found.
Issues 16/08/2026 22:58
- 4.5 — Sheet overruns one A4 page: The combined length of the Contraindications gate (11 items, lines 542–552), the Monitoring table (9 rows with long “Why” strings, lines 605–703), the Qualitative Assessment (6 multi-line entries, lines 716–734) and the At-A-Glance paragraph pushes the rendered sheet to roughly twice the height available on a 297mm page, rather than being condensed to the per-section budget.
Fixes 16/08/2026 22:58
- 4.5 — Contraindications gate condensed: Rewrote the four longest stop items to shed filler while keeping every qualifier — “Any chronic liver disease, including hepatitis B or C, cirrhosis (Child-Pugh Class A through C) and non-alcoholic fatty liver disease” became “Chronic liver disease (hepatitis B or C, cirrhosis Child-Pugh A–C, fatty liver)”, and the prior-injury, alcohol and pregnancy items were tightened the same way.
- 4.5 — Monitoring “Why” column tightened: Trimmed redundant words from the marker_2, marker_4, marker_5, marker_7 and marker_9 rationales (e.g. “Detects the cholestatic (bile-flow blockage) injury pattern seen in several kava case reports” → “…seen in kava case reports”), removing a wrapped line from several table rows.
- 4.5 — Monitoring targets and cadence shortened: Reduced marker_8_target to “Below 5 on the 7-item anxiety questionnaire”, marker_9_target to “No kava-specific target; tracked as change from own baseline”, and recast monitoring_cadence more compactly without dropping any scheduled draw or warning sign.
- 4.5 — Protocol and qualitative entries compacted: Shortened action_1_sub, action_3_sub, qualitative_item_2 and qualitative_item_6 by removing redundant wording, with no ER-sourced fact dropped.