Audit: QRS - Kutki for Health & Longevity
Audit conducted on 19/08/2026 12:10 using AI4L / Opus 5
Summary
| Items | Count |
|---|---|
| Total | 93 |
| Passed | 85 |
| Failed | 0 |
| N/A | 8 |
| Pass Rate | 100.00% |
- Total = Passed + Failed + N/A
- Pass Rate = Passed / (Passed + Failed) × 100
- N/A items are excluded from the pass rate calculation
1. General Rules
| # | Description | Result | Comments |
|---|---|---|---|
| 1.1 | Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. | 🟢 | All protocol, time-to-effect, benefit, risk, gate, monitoring and qualitative content traces to ER lines 351–361, 404, 145–211, 233–281, 317–329, 301–315, 432–456. |
| 1.2 | Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. | 🟢 | “whose promise the trials have yet to keep” and “unknown safety in pregnancy and lactation” mirror ER wording. |
| 1.3 | The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). | 🟢 | Contraindications retained at avoidance strength; cautions retained as cautions. |
| 1.4 | The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. | 🟢 | Gate items come only from Key Interactions & Contraindications; tiered cards only from Expected Benefits / Potential Risks & Side Effects. |
| 1.5 | PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. | 🟢 | No PMIDs, NCT identifiers, author names or brand names appear anywhere in the QRS. |
| 1.6 | The QRS does not introduce new attributions. | 🟢 | No attributions present. |
2. Focus, Tone & Audience
| # | Description | Result | Comments |
|---|---|---|---|
| 2.1 | The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. | 🟢 | Sober, evidence-gap-forward framing matches the ER Conclusion. |
| 2.2 | The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging | 🟢 | Quantified targets and defined actions are given without alarmism. |
| 2.3 | The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor | 🟢 | Content is stated as practice and evidence, not as orders. |
| 2.4 | The QRS avoids language that implies medical or clinical advice | 🟢 | No imperative clinical instructions in the document’s own voice. |
| 2.5 | The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” | 🟢 | No “recommended”, “should take”, or “advised” phrasing. |
| 2.6 | The QRS never addresses “the reader” directly — it presents evidence, not guidance | 🟢 | No second-person pronouns anywhere in the file. |
| 2.7 | The QRS is written in plain language, avoiding unnecessary medical jargon | 🟢 | Technical terms retained only where they are the decision-relevant fact (eGFR threshold, Child-Pugh class, CYP3A substrates). |
| 2.8 | Information is presented in a concise and very compact manner | 🟢 | Every gate, tier and table cell is a stripped noun phrase. |
| 2.9 | It DOES NOT address the reader directly | 🟢 | Confirmed; third-person throughout. |
| 2.10 | The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. | 🟢 | Functional ranges, batch testing and defined-course framing address this audience. |
| 2.11 | The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. | 🟢 | Whole-blood lead testing and MRI-based liver fat measurement are presented without hedging on effort. |
| 2.12 | The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. | 🟢 | Nine-marker monitoring panel is well beyond general-population framing. |
| 2.13 | Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. | 🟢 | At-a-glance conditions the value proposition on measurable liver abnormalities and a batch-tested product. |
| 2.14 | The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” (e.g., “American Academy of Anti-Aging Medicine”) are quoted verbatim. | 🟢 | The string “anti-aging” does not occur; the title uses “Longevity”. |
| 2.15 | The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. | 🟢 | “loose stools”, “cramping”, “biliary obstruction”, “cholecystitis” are the ER’s own clinical register. |
3. Template Integrity
| # | Description | Result | Comments |
|---|---|---|---|
| 3.1 | The following labels and headings on the QRS are fixed and not modified: Card and section headings: “Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”; Gate headings: “Contraindications”, “Key Interactions”; Tier labels: “High”, “Medium”, “Low”, “Speculative”; Table column headers in Monitoring: “Marker”, “Target”, “Why” | 🟢 | All fixed headings and tier labels are byte-identical to the template. |
| 3.2 | All “…” from the [qrs_template] are present in the the QRS. | 🟢 | All 34 template variables present; marker_#_* expanded to 1–9 and qualitative_item_# to 1–5. |
| 3.3 | Spans that are not addressed in a checklist item are left unchanged | 🟢 | Diff against the template shows changes confined to variable spans, the metadata block, and the two documented display: none toggles. |
4. Formatting
| # | Description | Result | Comments |
|---|---|---|---|
| 4.1 | When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” | N/A | No source ER section drawn on by the QRS is empty. |
| 4.2 | Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. | 🟢 | “Standard practitioner dose”, “Best time of day”, “Half-life and dose splitting” are verbatim ER bold labels (ER lines 351, 359, 361). |
| 4.3 | Labels are not paraphrased, abbreviated, or invented. | 🟢 | Monitoring row labels are verbatim ER table entries; time-to-effect labels use the ER’s own terms from the Time to effect bullet. |
| 4.4 | The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. | 🟢 | No emoji characters present; the ER’s “⚠️ Conflicted” marker was stripped. |
| 4.5 | The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. | 🟢 | Each section is condensed to its budget: gate rationales stripped, drug example lists trimmed, monitoring “why” cells reduced to a single clause. |
5. Metadata
| # | Description | Result | Comments |
|---|---|---|---|
| 5.1 | The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. | 🟢 | Lines 2–14, immediately after the doctype. |
| 5.2 | Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. | 🟢 | Opening --- at line 3, closing --- at line 13. |
| 5.3 | The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. | 🟢 | Contained wholly within the HTML comment; no duplicate on the page. |
| 5.4 | All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. | 🟢 | Only duration: "00:04" is quoted, and it contains a colon. |
| 5.5 | The filename of the source ER is stated as “er_filename: [er_filename]” | 🟢 | er_filename: kutki_2026-0825-0849_Opus_ER.md (line 4). |
| 5.6 | Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” | 🟢 | qrs_prompt_version: 26.7.02 matches QRS.md. |
| 5.7 | Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” (e.g., 2026-0501-1430) | 🟢 | qrs_creation_date: 2026-0819-1129. |
| 5.8 | The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” | 🟢 | qrs_creator_ai_nickname: Opus. |
| 5.9 | The nickname of the AI is just a single word model name without version, etc. (e.g., Opus, Sonnet, Grok, Gemini, ChatGPT) | 🟢 | Single word, no version. |
| 5.10 | The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” | 🟢 | qrs_creator_ai_fullname: Opus 5. |
| 5.11 | The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier (e.g., Opus 4.6, Sonnet 3.2, Grok 4.5, Gemini 3.1, ChatGPT 5.4) | 🟢 | “Opus 5” — nickname plus version, no qualifier. |
| 5.12 | The filename of the document is stated as “qrs_filename: [filename of this document]” | 🟢 | qrs_filename: kutki_2026-0825-0849_Opus_QRS.html matches the file on disk. |
| 5.13 | All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. | 🟢 | Re-verified across all nine keys; no stray whitespace or unnecessary quoting. |
6. Page Title & Header
| # | Description | Result | Comments |
|---|---|---|---|
| 6.1 | [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet” (e.g., “Intervention - Quick Reference Sheet”). The [canonical_topic] is HTML-entity-encoded as needed (e.g., & for &) |
🟢 | “Kutki for Health & Longevity - Quick Reference Sheet” (line 22). |
| 6.2 | [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed (e.g., & for &) |
🟢 | “Kutki for Health & Longevity” (line 417). |
| 6.3 | [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] | 🟢 | 2026-0819-1129 → “08/19/2026” (line 421). |
| 6.4 | [header_subline_model] is set to [qrs_creator_ai_fullname] | 🟢 | “Opus 5” (line 425). |
| 6.5 | No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. | 🟢 | Header holds only the title and the template subline; no alternate-names line despite the ER carrying one. |
7. At-A-Glance Section
| # | Description | Result | Comments |
|---|---|---|---|
| 7.1 | [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section |
🟢 | Condenses ER lines 480–484 into evidence state, tolerability, supply-chain hazard and the conditional value proposition. |
| 7.2 | [at_a_glance] is no longer than 60 words | 🟢 | Exactly 60 words. |
| 7.3 | Every fact in [at_a_glance] is supported by a distinct passage in the ER. | 🟢 | Animal-vs-human gap (ER 480), loose stools/cramping (ER 482), metals and substitution (ER 482), low-cost short-course framing (ER 484). |
| 7.4 | It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead | 🟢 | No acronyms; “toxic metals”, “loose stools”, “batch-tested” are all lay-usable terms. |
| 7.5 | It DOES NOT cite specific trials (names, years, sample sizes, p-values) | 🟢 | No trial names, years or sample sizes. |
| 7.6 | It DOES NOT cite effect sizes, relative risks, or statistical results | 🟢 | No numbers of any kind. |
8. Contraindications
| # | Description | Result | Comments |
|---|---|---|---|
| 8.1 | The section is derived from the ER Key Interactions & Contraindications section |
🟢 | Sourced from “Populations who should avoid Kutki” (ER lines 317–329). |
| 8.2 | [stop_items] represent the Contraindications from the ER | 🟢 | All six ER avoid-populations are present, none added. |
| 8.3 | Individual [stop_items] are formatted as <li></li> | 🟢 | Six <li> elements inside the span (lines 566–573). |
| 8.4 | Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. | 🟢 | Rationales such as “given absent reproductive toxicology data” and “for whom no dosing or safety data exist” are stripped; no dash-trailing clauses remain. |
| 8.5 | Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). | 🟢 | “Child-Pugh Class B or C”, “below 30 mL/min/1.73 m²”, “under 18”, and “(tacrolimus, ciclosporin)” all retained. |
| 8.6 | When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. | N/A | The ER uses no ranking notation inside parentheses in this section. |
| 8.7 | The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no population, condition, or scenario for which the intervention should be avoided, deferred, or used only under specialist supervision. |
🟢 | The ER names six such populations, and the section is correctly populated rather than empty. |
| 8.8 | If the section is left empty, an HTML comment inside the [stop_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. | N/A | The section is not empty. |
9. Key Interactions
| # | Description | Result | Comments |
|---|---|---|---|
| 9.1 | The section is derived from the ER Key Interactions & Contraindications section |
🟢 | Sourced from ER lines 301–315. |
| 9.2 | [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications | 🟢 | All eight ER interaction bullets are represented; none duplicates an avoid-population entry. |
| 9.3 | Individual [caution_items] are formatted as <li></li> | 🟢 | Eight <li> elements inside the span (lines 581–588). |
| 9.4 | Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. | 🟢 | Severity verdicts (“Caution”, “Monitor”) and mitigation sentences are stripped; the ER’s “Other interventions — “ dash prefix is removed. |
| 9.5 | Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). | 🟢 | Every ER drug list is retained in trimmed form; none dropped entirely. |
| 9.6 | When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. | N/A | The ER uses no ranking notation inside parentheses in this section. |
| 9.7 | The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no interaction, additive effect, or exposure that changes how the intervention is used. |
🟢 | The ER names eight such interactions, and the section is correctly populated rather than empty. |
| 9.8 | If the section is left empty, an HTML comment inside the [caution_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. | N/A | The section is not empty. |
10. Protocol
| # | Description | Result | Comments |
|---|---|---|---|
| 10.1 | The section is derived from the ER Protocol section |
🟢 | Sourced from ER Therapeutic Protocol, lines 351, 359, 361. |
| 10.2 | The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section |
🟢 | Dose, timing and dose-splitting are the three executable levers; the remaining ER bullets are alternatives, attributions or modifiers. |
| 10.3 | If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. | N/A | The ER supplies more than three actionable aspects; all three sets are used. |
| 10.4 | All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. |
🟢 | All nine cells carry ER-derived content (lines 450–483). |
11. Time to Effect
| # | Description | Result | Comments |
|---|---|---|---|
| 11.1 | The three sets of [time] items cover the three most important time-to-effect aspects from the ER | 🟢 | The ER states only two time-to-effect aspects (acute hepatitis, liver fat); both are covered. |
| 11.2 | The sets are picked and ordered by the magnitude of the related benefit | 🟢 | Acute viral hepatitis (Medium tier) precedes liver fat (Low tier). |
| 11.3 | If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. | 🟢 | The third .pcell carries style="display: none" and its three spans are empty (lines 518–528). |
| 11.4 | All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. | 🟢 | Values from ER line 404; time_1_sub magnitude from ER line 155. |
| 11.5 | If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel |
N/A | The ER does provide time-to-effect information (ER line 404). |
12. Benefits
| # | Description | Result | Comments |
|---|---|---|---|
| 12.1 | The section is derived from the ER Expected Benefits section |
🟢 | Sourced from ER lines 145–211. |
| 12.2 | Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] | 🟢 | All four variables present and correctly tiered. |
| 12.3 | Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. | 🟢 | Each entry is the ER’s benefit heading reduced to a noun phrase; magnitudes and citations dropped. |
| 12.4 | Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. | 🟢 | No parentheses remain in any benefits item. |
| 12.5 | If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. | 🟢 | The ER has no High-tier benefit; benefits_high carries style="display: none" with an empty list item (lines 536–538). |
13. Risks
| # | Description | Result | Comments |
|---|---|---|---|
| 13.1 | The section is derived from the ER Potential Risks & Side Effects section |
🟢 | Sourced from ER lines 229–281. |
| 13.2 | Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] | 🟢 | All four variables present and correctly tiered. |
| 13.3 | Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. | 🟢 | The 20.7% contamination figure, the 936-case pooled data and all citations are stripped. |
| 13.4 | Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. | 🟢 | No parentheses remain in any risks item. |
| 13.5 | If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. | N/A | All four ER risk tiers carry items; no sub-section is empty. |
14. Monitoring
| # | Description | Result | Comments |
|---|---|---|---|
| 14.1 | The section is derived from the ER Monitoring section |
🟢 | Sourced from the ER Monitoring Protocol & Defining Success table (lines 434–444). |
| 14.2 | All measurable/quantifiable biomarkers from the Monitoring section are listed |
🟢 | All nine ER table rows present, with targets reproduced exactly. |
| 14.3 | [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. |
🟢 | Condensed from ER line 432; carries all three intervals. |
15. Qualitative Assessment
| # | Description | Result | Comments |
|---|---|---|---|
| 15.1 | The section is derived from the ER Monitoring section |
🟢 | Sourced from the ER’s qualitative-markers list (lines 448–456). |
| 15.2 | All subjective/qualitative biomarkers from the Monitoring section are listed |
🟢 | All five ER qualitative markers are reproduced verbatim. |
Issues 19/08/2026 12:10
Pass rate 100.00%. No issues found.
Issues 19/08/2026 12:02
- 8.5 — Transplant drug examples dropped: The contraindication “Solid-organ transplant recipients on calcineurin inhibitors” (QRS line 573) drops the ER’s parenthetical “(anti-rejection drugs such as tacrolimus and ciclosporin)” (ER line 329) entirely rather than trimming it, removing the named drugs a reader uses to decide whether the gate applies.
Fixes 19/08/2026 12:02
- 8.5 — Transplant drug examples restored: The contraindication item now reads “Solid-organ transplant recipients on calcineurin inhibitors (tacrolimus, ciclosporin)”, restoring the ER’s parenthetical example drugs in trimmed form instead of dropping them entirely.
Issues 19/08/2026 11:55
- 4.5 — QRS overflows one A4 page: Stacked block height of the populated sheet is roughly 1,460pt against ~774pt of usable A4 height, driven by the uncondensed nine-row Monitoring table (lines 636-776), the eight-item Key Interactions gate (lines 582-600) and the long Protocol / Time-to-effect sub lines (lines 456-517).
- 2.8 — Verbose, redundant cell text:
time_1_sub(lines 500-503) repeats the value cell (“2–4 weeks” → “over two to four weeks”) before adding the bilirubin magnitude, andmarker_5_why,marker_7_why,marker_9_whyandmonitoring_cadencereproduce full ER sentences instead of compressed cell text.
Fixes 19/08/2026 11:55
- 4.5 / 2.8 — Monitoring “Why” column condensed: Shortened
marker_2_whythroughmarker_9_whyto compressed cell text (e.g.marker_5_whyfrom “Distinguishes bile duct obstruction from liver cell injury before a bile-moving herb is started” to “Distinguishes bile duct obstruction from liver cell injury”), cutting most rows to a single rendered line. - 4.5 / 2.8 — Monitoring cadence compressed: Reduced
monitoring_cadencefrom the ER’s full sentence to “Liver panel at 8–12 weeks, then every 6 months; glucose markers at 12 weeks if a glucose-lowering medication is taken; imaging only at 6–12 months”. - 2.8 — Time-to-effect redundancy removed: Replaced
time_1_subwith “Bilirubin fell to 2.5 mg/dL in 27.4 days versus 75.9 on placebo”, dropping the clause that restated the “2–4 weeks” value cell;time_2_subshortened to “Primary endpoint measured only at 24 weeks; months rather than days”. - 4.5 — Protocol sub lines shortened:
action_1_subtrimmed to “Extract users target 100–200 mg total picroside I plus II daily” andaction_3_subto “Plasma half-life one to four hours; single dosing leaves long unexposed intervals”. - 4.5 — Key Interactions parentheticals trimmed: Reduced each drug list to two or three examples and dropped the redundant “Over-the-counter” prefixes, keeping every interaction item and at least two named examples per 9.5.
Note: the eight Key Interactions, six Contraindications, nine monitoring biomarkers and five qualitative markers were all retained, since items 8.2, 9.2, 14.2 and 15.2 require complete coverage of the ER; the condensation above works within that constraint.
Issues 19/08/2026 11:48
- 11.1 / 11.3 — Duplicate time-to-effect aspect:
time_1(“Acute viral hepatitis”, 2–4 weeks, line 494) andtime_2(“Bilirubin decline”, 27.4 days, line 505) both describe biochemical recovery in the same acute viral hepatitis trial, so the panel covers only two distinct aspects while all three cells are populated instead of the unused set being left empty and hidden.
Fixes 19/08/2026 11:48
- 11.1 / 11.3 — Duplicate time-to-effect aspect: Merged the “Bilirubin decline / 27.4 days” cell into
time_1_subso the acute viral hepatitis aspect occupies a single cell, promoted “Liver fat / 24 weeks” totime_2, and left the now-unused third set empty withstyle="display: none".
Issues 19/08/2026 11:40
- 1.3 / 4.3 — Bilirubin label overstates ER: [time_2_label] at line 505 reads “Bilirubin normalisation”, but the ER (line 155) reports only a mean fall of total serum bilirubin to 2.5 mg/dL — well above the 0.3–1.0 mg/dL optimal range the QRS itself states at line 689 — so the invented label strengthens the ER claim.
Fixes 19/08/2026 11:40
- 1.3 / 4.3 — Bilirubin label overstates ER: Changed [time_2_label] from “Bilirubin normalisation” to “Bilirubin decline”, so the label matches the ER endpoint (a fall to 2.5 mg/dL) rather than implying a return to the normal range.
Issues 19/08/2026 11:35
- 1.3 — At-A-Glance strengthens ER claim: ER line 484 hedges with “kutki presents as a low-cost, short-course option whose promise the trials have yet to keep”; the QRS at line 437 asserts “it is a low-cost, short-course option”, dropping both the hedge and the closing caveat.
- 12.3 / 12.4 — Parenthetical qualifier in benefits: benefits_low (line 548) retains “(conflicted)” after “bronchial asthma symptom relief”; parenthetical content and tier qualifiers must be stripped because the Low tier already encodes evidence strength.
Fixes 19/08/2026 11:35
- 1.3 — At-A-Glance hedge restored: Changed “it is a low-cost, short-course option” to “it presents as a low-cost, short-course option whose promise the trials have yet to keep”, matching ER line 484; the opening and middle sentences were tightened to keep the section at 60 words (item 7.2).
- 12.3 / 12.4 — Parenthetical stripped from benefits: Removed “(conflicted)” after “bronchial asthma symptom relief” in benefits_low, leaving just the key fact.