Citrus peel oil: cheap, widely available, and rapidly broken down by the liver. Human evidence is thin — anxiety from inhaled cannabis blunted once, less tobacco staining on teeth, and heartburn relief resting on an unpublished study run by the seller. Documented harms, contact eczema from air-oxidised oil and nausea at gram doses, are clearer than the benefits. (Full Review)
| Marker | Target | Why |
|---|---|---|
| ALT | 10–26 U/L (men), 8–22 U/L (women) | Clearance is entirely hepatic; rising values signal strain |
| Creatinine with eGFR | eGFR above 90 mL/min/1.73 m² | Addresses the rat kidney question directly with human data |
| IGF-1 | 100–170 ng/mL, or age-adjusted middle of the reference range | The one supplementation change that runs against longevity goals |
| hs-CRP | Below 1.0 mg/L | Tracks the proposed anti-inflammatory benefit |
| HbA1c | 4.8–5.3% | Screens the speculative glucose claim against reality |
Cadence: Baseline before the first dose; a 20-day course needs no interim bloodwork; the panel is repeated once at four to eight weeks if use continues beyond a single course, then every six to twelve months for continuous use.