An edible mushroom whose compounds encourage nerve-cell growth and repair. The strongest human signal is modest memory improvement in older adults with early decline, fading once stopped. Weaker evidence supports easing low mood and anxiety, nerve repair, and gut health. Low-risk and low-cost, but its brain-protective promise remains genuine yet unproven. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Platelet count | 150–400 ×10⁹/L | Screens for bleeding risk given theoretical antiplatelet effect |
| Fasting glucose | 75–90 mg/dL | Detects additive glucose lowering in people on diabetes drugs |
| Hemoglobin A1c | < 5.4% | Reflects average blood sugar over ~3 months |
| hs-CRP | < 1.0 mg/L | Tracks systemic inflammation the mushroom may reduce |
| ALT | ≤ 25 U/L (men), ≤ 22 U/L (women) | Confirms liver tolerability during ongoing use |
Cadence: Baseline before starting, then at ~3 months, then every 6–12 months (sooner if combining with interacting medications)