Luteolin is a plant compound in celery, parsley, and chamomile studied for calming inflammation and steadying the immune cells behind allergic reactions. Laboratory and animal evidence is strong; human proof is thin and mostly from combination products. Poor absorption limits results. Generally well tolerated, with mild digestive upset most common. Longevity benefits remain unconfirmed rather than established. (Full Review)
| Marker | Target | Why |
|---|---|---|
| hs-CRP | < 1.0 mg/L | Tracks systemic inflammation |
| Fasting glucose | 75–90 mg/dL | Gauges metabolic response |
| HbA1c | < 5.4% | Reflects average blood sugar over ~3 months |
| TSH | 0.5–2.5 mIU/L | Screens for the theoretical thyroid effect |
| ALT | < 25 U/L (men) / < 20 U/L (women) | Monitors the liver, which metabolizes luteolin |
Cadence: Baseline, then recheck at 8–12 weeks, then every 6–12 months; more frequent for those on interacting medications or with thyroid or liver conditions