A well-absorbed, gentle form of an essential mineral. Its most solid value is restoring adequate magnesium levels, especially in older adults, those with digestive or metabolic conditions, and people on depleting medications. Blood pressure and blood-sugar handling improve modestly; benefits for sleep, mood, and cramps are mixed. Loose stools are the main drawback; reduced kidney function the key caution. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Serum magnesium | 0.85–1.0 mmol/L (2.1–2.4 mg/dL) | Confirms adequacy and screens for deficiency |
| Red blood cell magnesium | Upper half of the lab reference range | Better estimate of tissue magnesium stores |
| Kidney function (eGFR) | ≥60 mL/min/1.73m² | Safety — impaired clearance raises toxicity risk |
| Fasting glucose and HbA1c | Glucose 70–85 mg/dL; HbA1c <5.4% | Tracks the metabolic benefit in at-risk users |
| Blood pressure | <120/80 mmHg | Tracks the cardiovascular benefit |
Cadence: Baseline before starting; every 6–12 months for healthy adults; at 1–3 months after starting then periodically for those with reduced kidney function, diabetes, or on interacting medications