Audit: QRS - Maral Root for Health & Longevity

Audit conducted on 19/08/2026 20:53 using AI4L / Opus 5

Iterations

Summary

Items Count
Total 93
Passed 84
Failed 0
N/A 9
Pass Rate 100.00%
  • Total = Passed + Failed + N/A
  • Pass Rate = Passed / (Passed + Failed) × 100
  • N/A items are excluded from the pass rate calculation

1. General Rules

# Description Result Comments
1.1 Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. 🟢 Protocol, time-to-effect, benefit, risk, gate, marker and cadence content all trace to ER lines 124–463.
1.2 Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. 🟢 “never replicated” (time_2_sub), “No head-to-head comparison of schedules exists” (action_3_sub), “Nothing supports an acute or within-days effect” (time_3_sub) all mirror ER wording.
1.3 The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). 🟢 Contraindications remain contraindications; conflicted findings retain their qualifying clauses in the sub-cells.
1.4 The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. 🟢 Gates draw only from ER Key Interactions & Contraindications; tiers draw only from Expected Benefits / Potential Risks & Side Effects.
1.5 PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. 🟢 No PMIDs, citations, author names, NCT identifiers or brand names appear anywhere in the QRS.
1.6 The QRS does not introduce new attributions. 🟢 No attributions of any kind are present.

2. Focus, Tone & Audience

# Description Result Comments
2.1 The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. 🟢 Sceptical, evidence-weighted register matches the ER throughout.
2.2 The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging 🟢 Quantified thresholds paired with plain-language framing; no alarmism, no hype.
2.3 The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor 🟢 Cadence and protocol cells are stated as noun phrases, not directives.
2.4 The QRS avoids language that implies medical or clinical advice 🟢 No “should”, “must”, “recommend”, “consult” or comparable advisory verbs in the document voice.
2.5 The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” 🟢 All cells are descriptive statements of what the ER reports.
2.6 The QRS never addresses “the reader” directly — it presents evidence, not guidance 🟢 No second-person pronouns anywhere in the rendered content.
2.7 The QRS is written in plain language, avoiding unnecessary medical jargon 🟢 Technical terms are expanded on first use (ALT, AST, eGFR, hs-CRP, HbA1c, IGF-1, DXA).
2.8 Information is presented in a concise and very compact manner 🟢 Gate items and tier items are stripped to the key fact; no mechanistic rationale carried over.
2.9 It DOES NOT address the reader directly 🟢 Confirmed by scan for “you”/”your”; no matches.
2.10 The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. 🟢 Optimal functional ranges, DXA tracking and volume-load logging address exactly this audience.
2.11 The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. 🟢 Eleven-marker panel, twice-weekly home blood pressure and structured resistance training assume high willingness.
2.12 The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. 🟢 No simplified general-population framing; content assumes lab access and training discipline.
2.13 Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. 🟢 At-a-glance closes on product-quality failure, the decisive issue for a self-experimenting audience.
2.14 The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” (e.g., “American Academy of Anti-Aging Medicine”) are quoted verbatim. 🟢 “Longevity” is used in the title; “anti-aging” does not appear.
2.15 The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. 🟢 Clinical register throughout; the plain-language terms in at-a-glance are mandated by 7.4 and are the ER’s own conclusion wording.

3. Template Integrity

# Description Result Comments
3.1 The following labels and headings on the QRS are fixed and not modified: Card and section headings: “Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”; Gate headings: “Contraindications”, “Key Interactions”; Tier labels: “High”, “Medium”, “Low”, “Speculative”; Table column headers in Monitoring: “Marker”, “Target”, “Why” 🟢 All headings, gate titles, tier labels and column headers are byte-identical to the template.
3.2 All “” from the [qrs_template] are present in the the QRS. 🟢 72 unique variable spans present, including 11 marker triplets and 5 qualitative items expanded from the template’s “#” patterns.
3.3 Spans that are not addressed in a checklist item are left unchanged 🟢 website="evidence_review", website="audit" and website="full_review" spans, the disclaimer and all CSS are untouched.

4. Formatting

# Description Result Comments
4.1 When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” N/A No source ER section used by the QRS is empty.
4.2 Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. 🟢 “Standard extract protocol”, “Best time of day”, “Single versus split dosing” are the ER’s bold labels verbatim; interaction items carry the ER’s bold labels.
4.3 Labels are not paraphrased, abbreviated, or invented. 🟢 Marker names are verbatim from the ER monitoring table; protocol labels verbatim from ER Therapeutic Protocol.
4.4 The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. 🟢 Unicode scan returns no emoji; tiering is carried by CSS classes and bold tier labels.
4.5 The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. 🟢 Every section is condensed against its ER source to the per-section budget; no section reproduces ER prose at length.

5. Metadata

# Description Result Comments
5.1 The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. 🟢 Lines 2–14, immediately after the doctype and before any other markup.
5.2 Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. 🟢 Opening --- at line 3, closing --- at line 13; the title text on line 2 precedes the block.
5.3 The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. 🟢 Contained entirely in an HTML comment; no duplicate rendering elsewhere.
5.4 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Only duration: "00:04" is quoted, correctly, because it contains a colon.
5.5 The filename of the source ER is stated as “er_filename: [er_filename]” 🟢 Line 4: er_filename: maral_root_2026-0825-1818_Opus_ER.md.
5.6 Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” 🟢 Line 5: qrs_prompt_version: 26.7.02, matching QRS.md.
5.7 Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” (e.g., 2026-0501-1430) 🟢 Line 6: qrs_creation_date: 2026-0819-2038.
5.8 The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” 🟢 Line 7: qrs_creator_ai_nickname: Opus.
5.9 The nickname of the AI is just a single word model name without version, etc. (e.g., Opus, Sonnet, Grok, Gemini, ChatGPT) 🟢 “Opus” — single word, no version.
5.10 The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” 🟢 Line 8: qrs_creator_ai_fullname: Opus 5.
5.11 The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier (e.g., Opus 4.6, Sonnet 3.2, Grok 4.5, Gemini 3.1, ChatGPT 5.4) 🟢 “Opus 5” — nickname plus version, no qualifier.
5.12 The filename of the document is stated as “qrs_filename: [filename of this document]” 🟢 Line 9 matches the actual file name maral_root_2026-0825-1818_Opus_QRS.html.
5.13 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Re-verified across all ten keys; no stray whitespace or unnecessary quoting.

6. Page Title & Header

# Description Result Comments
6.1 [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet” (e.g., “Intervention - Quick Reference Sheet”). The [canonical_topic] is HTML-entity-encoded as needed (e.g., &amp; for &) 🟢 Line 22: “Maral Root for Health & Longevity - Quick Reference Sheet”.
6.2 [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed (e.g., &amp; for &) 🟢 Line 417: “Maral Root for Health & Longevity”.
6.3 [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] 🟢 Line 421: “08/19/2026”, from qrs_creation_date: 2026-0819-2038.
6.4 [header_subline_model] is set to [qrs_creator_ai_fullname] 🟢 Line 425: “Opus 5”.
6.5 No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. 🟢 Header contains only the title and the template subline; no alternate-names line despite the ER carrying one.

7. At-A-Glance Section

# Description Result Comments
7.1 [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section 🟢 Four sentences tracking ER lines 485–489: mechanism, split human evidence, unreplicated animal work, product-quality failure.
7.2 [at_a_glance] is no longer than 60 words 🟢 59 words.
7.3 Every fact in [at_a_glance] is supported by a distinct passage in the ER. 🟢 Mechanism ← ER 126/485; conflicting trials ← ER 487; unreplicated animal work ← ER 487; label and contamination failure ← ER 489.
7.4 It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead 🟢 “plant steroid”, “blood sugar”, “blood fats”, “blood-vessel inflammation” — no acronyms, no specialist classifications.
7.5 It DOES NOT cite specific trials (names, years, sample sizes, p-values) 🟢 Trials are referred to only as “one training study” and “another”.
7.6 It DOES NOT cite effect sizes, relative risks, or statistical results 🟢 No numeric effect measures appear.

8. Contraindications

# Description Result Comments
8.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 All seven items map to the “Populations who should avoid Maral Root” list at ER 326–333.
8.2 [stop_items] represent the Contraindications from the ER 🟢 All six ER bullets are represented; the combined hypertension/seizure bullet is split into two items.
8.3 Individual [stop_items] are formatted as <li></li> 🟢 Seven <li> elements inside the stop_items span, lines 540–546.
8.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 Every ER em-dash rationale (“— the proposed mechanism is estrogen-receptor activation”, “— additive antiplatelet effect”, etc.) is stripped.
8.5 Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 “(breast, endometrial, ovarian)”, “(resting blood pressure above 160/100 mmHg)”, “(eGFR below 30 mL/min/1.73 m²)” and the 10-day surgical window are all retained.
8.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. N/A The ER uses no ranking notation in its contraindication parentheticals.
8.7 The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no population, condition, or scenario for which the intervention should be avoided, deferred, or used only under specialist supervision. 🟢 The ER names six avoid-populations, and the section is correctly populated rather than empty.
8.8 If the section is left empty, an HTML comment inside the [stop_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. N/A The section is not empty.

9. Key Interactions

# Description Result Comments
9.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 All seven items map to the interaction bullets at ER 310–324.
9.2 [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications 🟢 Anticoagulants (warfarin, apixaban) are correctly dropped because “therapeutic anticoagulation” is a contraindication; the creatine/whey/leucine bullet is excluded because the ER states “No interaction risk identified”.
9.3 Individual [caution_items] are formatted as <li></li> 🟢 Seven <li> elements inside the caution_items span, lines 554–560.
9.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 “Caution.” markers, mechanism sentences and “Mitigation:” clauses are all stripped; the “Supplement interactions —” prefixes are removed.
9.5 Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 All named example drugs and botanicals are preserved verbatim, including the italicised binomials for the adaptogens.
9.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. N/A The ER uses no ranking notation in its interaction parentheticals.
9.7 The section is left empty ONLY IF the ER’s Key Interactions & Contraindications section identifies no interaction, additive effect, or exposure that changes how the intervention is used. 🟢 The ER names multiple additive-effect interactions, and the section is correctly populated.
9.8 If the section is left empty, an HTML comment inside the [caution_items] span records the ER basis for the absence, naming or quoting the ER text relied on. E.g. N/A The section is not empty.

10. Protocol

# Description Result Comments
10.1 The section is derived from the ER Protocol section 🟢 All three cells trace to ER Therapeutic Protocol lines 355, 363 and 367.
10.2 The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section 🟢 Dose/standardisation, timing and dosing schedule are the three executable levers in the ER protocol list.
10.3 If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. N/A The ER supplies well over three actionable aspects; all three sets are used.
10.4 All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. 🟢 All nine cells carry substantive ER-derived content; no placeholders remain.

11. Time to Effect

# Description Result Comments
11.1 The three sets of [time] items cover the three most important time-to-effect aspects from the ER 🟢 Muscle/strength onset (ER 412), Giardia clearance at ten days (ER 186), and the absence of an acute effect (ER 412).
11.2 The sets are picked and ordered by the magnitude of the related benefit 🟢 Medium-tier muscle benefit first, Low-tier Giardia clearance second, the null acute case last.
11.3 If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. N/A Three distinct time-to-effect aspects exist and all three sets are used.
11.4 All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. 🟢 All nine cells carry ER-derived content with the qualifying clauses preserved in the sub-cells.
11.5 If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel N/A The ER provides explicit time-to-effect information at line 412.

12. Benefits

# Description Result Comments
12.1 The section is derived from the ER Expected Benefits section 🟢 All twelve listed benefits correspond one-to-one with ER benefit headings at lines 144–210.
12.2 Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] 🟢 All four spans present, lines 521–530.
12.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Each entry is the ER benefit heading alone; magnitude paragraphs and “⚠️ Conflicted” markers are not carried over.
12.4 Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 The ER’s “(age-related muscle loss)” gloss and all other parentheticals are stripped.
12.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. 🟢 The ER has no High-tier benefit; line 521 carries an empty benefits_high span with style="display: none".

13. Risks

# Description Result Comments
13.1 The section is derived from the ER Potential Risks & Side Effects section 🟢 All ten listed risks correspond one-to-one with ER risk headings at lines 232–292.
13.2 Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] 🟢 All four spans present, lines 572–583.
13.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Each entry is the ER risk heading alone; the magnitude figures (12%, 40%, 13.5%) are not carried over.
13.4 Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 No parenthetical content appears in any risk entry.
13.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. N/A The ER populates all four risk tiers, so no sub-section needs hiding.

14. Monitoring

# Description Result Comments
14.1 The section is derived from the ER Monitoring section 🟢 Derived from ER Monitoring Protocol & Defining Success, lines 440–454.
14.2 All measurable/quantifiable biomarkers from the Monitoring section are listed 🟢 All eleven ER biomarker rows are present in ER order, with targets and rationales carried over verbatim.
14.3 [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. 🟢 Line 724 reproduces the ER’s baseline, 6–8 week, 6-month, 12-week and twice-weekly blood-pressure schedule.

15. Qualitative Assessment

# Description Result Comments
15.1 The section is derived from the ER Monitoring section 🟢 Derived from the “Qualitative markers worth tracking alongside the labs” list at ER 456–462.
15.2 All subjective/qualitative biomarkers from the Monitoring section are listed 🟢 All five qualitative markers are present; the sixth ER bullet is a success definition, not a qualitative marker.

Issues 19/08/2026 20:53

Pass rate 100.00%. No issues found.

Issues 19/08/2026 20:50

  1. 1.1 — Time-to-effect range not in ER: [time_1_value] reads “8–10 weeks” (QRS line 486), but the ER states only that “the earliest separation from placebo appeared around 8 weeks” (ER line 412); no 8–10 week window appears anywhere in the ER.

Fixes 19/08/2026 20:50

  1. 1.1 — Time-to-effect range not in ER: Changed [time_1_value] from “8–10 weeks” to “Around 8 weeks” so the stated time to effect matches the ER’s “the earliest separation from placebo appeared around 8 weeks”.

Issues 19/08/2026 20:44

  1. 1.2 — Hedge dropped in At-A-Glance: The At-A-Glance line 433 states animal work “has not been repeated in people”, while the ER Conclusion (line 487) says “almost none of it has been repeated in people”; the QRS drops the ER’s hedge and states an absolute.

Fixes 19/08/2026 20:44

  1. 1.2 — At-A-Glance hedge restored: Changed “has not been repeated in people” to “has almost never been repeated in people”, matching the ER Conclusion hedge (“almost none of it has been repeated in people”); At-A-Glance stays within the 60-word budget at 59 words.