An injectable peptide that darkens skin without sun while raising sexual desire, triggering erections, and blunting appetite. These effects are real but the evidence is thin. Serious harms — changing moles and skin cancer, prolonged painful erections, raised blood pressure, and unregulated purity — weigh heavily against a mostly cosmetic reward. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Blood pressure | <120/80 mmHg | Peptide can raise blood pressure; screens for pressor effect |
| Full-body skin / mole mapping | No new or changing atypical lesions | Detects mole darkening, enlargement, or new nevi that could mask or signal melanoma |
| Resting heart rate | 50–70 bpm | Screens for cardiovascular strain alongside blood pressure |
| Renal function (creatinine, eGFR) | eGFR >90 mL/min/1.73 m² | Screens for the rare renal infarction/rhabdomyolysis risk |
Cadence: Skin and blood pressure at baseline; recheck blood pressure at 1–2 weeks after initiation and periodically thereafter; dermatologic skin checks every 6–12 months (sooner if any mole changes).