A laboratory-made copy of the body's own pigment signal. It darkens skin reliably and, in men, also triggers erections and raises sexual desire. Against that sit near-universal nausea, unwanted erections, rising blood pressure, and moles that darken and multiply, hiding the early warning signs of skin cancer. Nothing sold is made to any quality standard. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Mapped naevus count and dermoscopy | No new or evolving lesions | Preserves melanoma surveillance |
| Resting blood pressure | Below 120/80 mmHg | Captures the sympathetic pressor effect |
| Resting heart rate | 50–65 bpm | Tracks sympathetic activation |
| Creatine kinase (CK) | 60–200 U/L | Detects muscle breakdown early |
| Serum creatinine and eGFR | Creatinine 0.7–1.1 mg/dL; eGFR above 90 | Detects kidney injury |
| Fasting insulin and HOMA-IR | Insulin 2–5 µIU/mL; HOMA-IR under 1.5 | Tests the speculative metabolic claim |
| 25-hydroxyvitamin D | 40–60 ng/mL | A pharmacological tan makes no vitamin D |
| Total and free testosterone (men) | Total 600–900 ng/dL; free 15–25 ng/dL | Establishes whether an erectile complaint is hormonal |
Cadence: Blood pressure pre- and 2 h post-dose daily for two weeks, then weekly; laboratory testing at baseline, 4 and 12 weeks; dermatological review at 3 months, then every 6–12 months for at least three years after the last dose.