A natural energy-cycle molecule now sold as a heat-stabilized supplement. Human evidence is strongest, though still early, for easing the lasting fatigue that can follow viral infections. Longevity claims rest on worm studies that a careful mouse study did not confirm. Generally well tolerated short-term; long-term safety is untested. (Full Review)
| Marker | Target | Why |
|---|---|---|
| Fasting glucose | 75–90 mg/dL | Screens for the theoretical blood-sugar-lowering effect |
| HbA1c | < 5.4% | Captures longer-term glucose trends beyond a single reading |
| Fasting insulin | 2–5 µIU/mL | Gauges metabolic health and insulin sensitivity |
| ALT | < 25 U/L | General safety check for an ongoing oral supplement |
| hs-CRP | < 1.0 mg/L | Tracks inflammation, one of the proposed mechanistic targets |
Cadence: Baseline before first dose; recheck at 4–8 weeks, then every 6–12 months; more frequent glucose checks in the first weeks if on glucose-lowering medication