Brief magnetic pulses induce tiny electrical currents in tissue. Blinded trials support modest pain relief in knee and hand arthritis, in long-standing back pain, and after surgery, plus better balance and walking speed in older adults with thinning bones. Outside that band the record thins quickly. Side effects match dummy devices; the real costs are money and months. (Full Review)
| Marker | Target | Why |
|---|---|---|
| 25-Hydroxyvitamin D | 40–60 ng/mL | Bone response depends on adequate substrate |
| Serum CTX | Lower half of the age- and sex-specific reference range | Tracks the rate of bone breakdown |
| Serum P1NP | 30–60 ng/mL in adults not on bone drugs | Tracks the rate of new bone formation |
| Bone mineral density (DXA T-score) | T-score above −1.0 | The endpoint any bone-directed course targets |
| hs-CRP | Below 0.9 mg/L | Systemic inflammation, the proposed target of the anti-inflammatory mechanism |
| Serum calcium (albumin-corrected) | 9.2–10.0 mg/dL | Rules out a calcium disorder that would confound bone results |
| Parathyroid hormone | 15–35 pg/mL | Detects the hormonal driver of bone loss that PEMF cannot address |
Cadence: Baseline before the first session; symptom score repeated at 4 and 8 weeks; inflammation and bone turnover markers rechecked at 3 months; bone density imaging repeated no sooner than 12 months; whole course reassessed at 8–12 weeks against the baseline symptom score