{
  "slug": "rapamycin",
  "topic": "Rapamycin for Health & Longevity",
  "url": "https://evipedia.ai/rapamycin",
  "datePublished": "2026-07-10",
  "dateModified": "2026-07-10",
  "lastReviewed": "2026-07-10",
  "about": {
    "type": "Drug",
    "name": "Rapamycin",
    "alternateName": [
      "Sirolimus",
      "Rapamune",
      "AY-22989",
      "WY-090217"
    ]
  },
  "citation": [
    {
      "name": "Targeting ageing with rapamycin and its derivatives in humans: a systematic review",
      "url": "https://pubmed.ncbi.nlm.nih.gov/38310895/",
      "pmid": "38310895"
    },
    {
      "name": "Meta-Analysis of 29 Experiments Evaluating the Effects of Rapamycin on Life Span in the Laboratory Mouse",
      "url": "https://pubmed.ncbi.nlm.nih.gov/27519886/",
      "pmid": "27519886"
    },
    {
      "name": "Rapamycin, Not Metformin, Mirrors Dietary Restriction-Driven Lifespan Extension in Vertebrates: A Meta-Analysis",
      "url": "https://pubmed.ncbi.nlm.nih.gov/40532901/",
      "pmid": "40532901"
    },
    {
      "name": "Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis",
      "url": "https://pubmed.ncbi.nlm.nih.gov/36399256/",
      "pmid": "36399256"
    },
    {
      "name": "The effect of rapamycin and its analogues on age-related musculoskeletal diseases: a systematic review",
      "url": "https://pubmed.ncbi.nlm.nih.gov/35861940/",
      "pmid": "35861940"
    },
    {
      "name": "NCT05949658",
      "url": "https://clinicaltrials.gov/study/NCT05949658"
    },
    {
      "name": "NCT05835999",
      "url": "https://clinicaltrials.gov/study/NCT05835999"
    },
    {
      "name": "NCT06727305",
      "url": "https://clinicaltrials.gov/study/NCT06727305"
    },
    {
      "name": "NCT05836025",
      "url": "https://clinicaltrials.gov/study/NCT05836025"
    },
    {
      "name": "NCT04488601",
      "url": "https://clinicaltrials.gov/study/NCT04488601"
    }
  ]
}