Audit: QRS - Silica for Health & Longevity

Audit conducted on 26/06/2026 04:39 using AI4L / Opus 4.8

Iterations

Summary

Items Count
Total 91
Passed 91
Failed 0
N/A 0
Pass Rate 100.00%
  • Total = Passed + Failed + N/A
  • Pass Rate = Passed / (Passed + Failed) × 100
  • N/A items are excluded from the pass rate calculation

1. General Rules

# Description Result Comments
1.1 Every claim, magnitude, label, recommendation, and statement in the QRS is literally supported by content in the source ER. 🟢 All benefit, risk, protocol, monitoring, and gate content traces directly to ER sections.
1.2 Where the ER uses cautious phrasing (“not formally studied”, “None documented in human trials to date”, “theoretical concern”, “data are limited”), the QRS uses the same phrasing. 🟢 “mixed and unconfirmed by large trials” mirrors ER conclusion; cautious framing preserved.
1.3 The QRS never strengthens an ER claim (e.g., “not formally studied” → “not required”) or softens one (e.g., “do not use during pregnancy” → “use with caution during pregnancy”). 🟢 “not advised” and “limit supplemental silicon beyond food” match ER line 239 wording.
1.4 The QRS does not relabel an ER fact under a different decision category. A “Benefit-Modifying Factor” from ER section is not surfaced as a “Caution”; a “Risk-Modifying Factor” is not surfaced as a “Side Effect”; etc. 🟢 Contraindications and interactions both derive from the ER “Key Interactions & Contraindications” section.
1.5 PubMed IDs, study citations, expert names, clinical trial identifiers (NCT*), and brand names appear in the QRS only if they appear in the source ER for the same fact. 🟢 Only “BioSil” / “ch-OSA” appear, both present in the ER protocol section.
1.6 The QRS does not introduce new attributions. 🟢 No new sources or authorities introduced.

2. Focus, Tone & Audience

# Description Result Comments
2.1 The QRS follows the tone of the ER, which is determined by the ER’s own language, phrasing, and framing. 🟢 Objective, evidence-graded tone consistent with ER.
2.2 The tone of the QRS is simultaneously expert, accessible, objective, and data-driven, but also empowering and encouraging 🟢 Tone is expert yet accessible throughout.
2.3 The QRS reads as a trusted, knowledgeable guide rather than a prescriptive doctor 🟢 Presents evidence without prescription.
2.4 The QRS avoids language that implies medical or clinical advice 🟢 No directive/advisory language.
2.5 The QRS “presents information” instead of “providing guidance”, “recommending”, or “advising” 🟢 Information presented, not advised.
2.6 The QRS never addresses “the reader” directly — it presents evidence, not guidance 🟢 No second-person address.
2.7 The QRS is written in plain language, avoiding unnecessary medical jargon 🟢 Plain language; technical terms explained in monitoring context.
2.8 Information is presented in a concise and very compact manner 🟢 Compact cells and bullets.
2.9 It DOES NOT address the reader directly 🟢 No “you/your” in body content.
2.10 The target audience is health- and longevity-oriented adults who are risk-aware, proactive, and actively seeking to optimize health or apply the intervention under review. 🟢 Framing fits longevity-oriented audience.
2.11 The target audience is willing to employ lifestyle and behavioral changes as well as follow protocols that may be inconvenient, costly, or require effort. 🟢 Protocol and dietary alternatives presented accordingly.
2.12 The document is NOT written for the general population, who are unwilling to employ lifestyle and behavioral changes or follow protocols that may be inconvenient, costly, or require effort. 🟢 Content assumes a proactive reader.
2.13 Framing, takeaways, and risk/benefit weighting throughout the document reflect this audience, including where an intervention’s signal for the average person differs from its signal for this audience. 🟢 Evidence tiers and weighting reflect this audience.
2.14 The document’s own voice frames usage in longevity terms, not “anti-aging” (e.g., “anti-aging clinics”, “anti-aging community”, “anti-aging medicine”). Proper names that contain “anti-aging” (e.g., “American Academy of Anti-Aging Medicine”) are quoted verbatim. 🟢 “Health & Longevity” framing; no “anti-aging” usage.
2.15 The document’s own voice uses formal clinical and scientific terminology, not colloquial or consumer-grade language (e.g., “oral medication” not “pill(s)”; “injection” not “shot”; “adverse event” not “bad reaction”). Direct quotes from sources are exempt. 🟢 Uses “oral supplement”, “supplementation”; no colloquial terms.

3. Template Integrity

# Description Result Comments
3.1 The following labels and headings on the QRS are fixed and not modified: Card and section headings (“Protocol”, “Time to effect”, “Benefits”, “Risk & Side Effects”, “Monitoring”, “Qualitative Assessment”); Gate headings (“Contraindications”, “Key Interactions”); Tier labels (“High”, “Medium”, “Low”, “Speculative”); Table column headers in Monitoring (“Marker”, “Target”, “Why”). 🟢 All fixed headings and labels present unmodified.
3.2 All “” from the [qrs_template] are present in the the QRS. 🟢 All expected data-qrs-var spans present.
3.3 Spans that are not addressed in a checklist item are left unchanged 🟢 Untouched spans remain intact (e.g., website placeholders).

4. Formatting

# Description Result Comments
4.1 When the source ER section is empty, the QRS uses the ER’s own empty-state phrasing verbatim. Typical phrasings are “None documented in human trials to date” and “Not formally studied” 🟢 No empty source sections; benefits_high/risks_high/risks_medium correctly set to display:none.
4.2 Where the ER presents a bulleted item as “Label: content”, the QRS uses the ER’s bold label verbatim as the cell or row label. 🟢 Tier and monitoring labels mirror ER labels.
4.3 Labels are not paraphrased, abbreviated, or invented. 🟢 Labels faithful to ER.
4.4 The QRS DOES NOT use emoji indicators (no 🟩, 🟥, 🟨, etc.). Color and emphasis are conveyed through CSS and bold labels. 🟢 No emoji indicators in QRS.
4.5 The QRS is designed to render on one A4 page. Any section that has more content in the ER than fits the per-section budget is condensed by the LLM, not extended onto a second page. 🟢 Content condensed to a single-page layout.

5. Metadata

# Description Result Comments
5.1 The metadata is placed inside a single HTML comment that is the first element after “<!doctype html>” and before any other comment, head, or body content. 🟢 Comment block is first element after doctype.
5.2 Inside that HTML comment the YAML block is delimited by a line “—” opening and a line “—” closing. Text before the opening “—” is permitted but is not parsed as YAML. 🟢 YAML delimited by — pair.
5.3 The metadata is not visible in any rendered view of the QRS and is not surfaced by any other element on the sheet. 🟢 Inside HTML comment; not rendered.
5.4 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Values trimmed; only duration quoted (contains colon).
5.5 The filename of the source ER is stated as “er_filename: [er_filename]” 🟢 er_filename: silica_2026-0626-0352_Opus_ER.md
5.6 Version of the QRS.md file used to create the document is stated as “qrs_prompt_version: [Version of QRS.md]” 🟢 qrs_prompt_version: 26.5.18 matches QRS.md.
5.7 Creation date and time of the document is stated as “qrs_creation_date: [YYYY-MMDD-HHMM]” (e.g., 2026-0501-1430) 🟢 qrs_creation_date: 2026-0626-0352.
5.8 The nickname of the AI used to create the document is stated as “qrs_creator_ai_nickname: [qrs_creator_ai_nickname]” 🟢 qrs_creator_ai_nickname: Opus.
5.9 The nickname of the AI is just a single word model name without version, etc. (e.g., Opus, Sonnet, Grok, Gemini, ChatGPT) 🟢 “Opus” single word.
5.10 The full name of the AI used to create the document is stated as “qrs_creator_ai_fullname: [qrs_creator_ai_fullname]” 🟢 qrs_creator_ai_fullname: Opus 4.8.
5.11 The full name of the AI consists of the [qrs_creator_ai_nickname] and the model version number and no additional qualifier (e.g., Opus 4.6, Sonnet 3.2, Grok 4.5, Gemini 3.1, ChatGPT 5.4) 🟢 “Opus 4.8” with no extra qualifier.
5.12 The filename of the document is stated as “qrs_filename: [filename of this document]” 🟢 qrs_filename: silica_2026-0626-0352_Opus_QRS.html.
5.13 All frontmatter values are trimmed: no leading or trailing whitespace, no surrounding quotes unless the value contains a colon, bracket, or leading special character that requires YAML quoting. 🟢 Frontmatter clean and consistent.

6. Page Title & Header

# Description Result Comments
6.1 [page_title] is set to the [canonical_topic] of the ER frontmatter followed by “ - Quick Reference Sheet” (e.g., “Intervention - Quick Reference Sheet”). The [canonical_topic] is HTML-entity-encoded as needed (e.g., &amp; for &) 🟢 “Silica for Health & Longevity - Quick Reference Sheet”.
6.2 [header_topic] is set to the [canonical_topic] of the ER frontmatter, with HTML entities encoded as needed (e.g., &amp; for &) 🟢 “Silica for Health & Longevity”.
6.3 [header_subline_date] is set to [qrs_creation_date reformatted as MM/DD/YYYY] 🟢 “06/26/2026” from 2026-0626.
6.4 [header_subline_model] is set to [qrs_creator_ai_fullname] 🟢 “Opus 4.8”.
6.5 No additional header content appears: no badge, version stamp, AKA / alternate names line, source-AI attribution, audit date, or QRS variant marker. 🟢 Header contains only standard subline elements.

7. At-A-Glance Section

# Description Result Comments
7.1 [at_a_glance] is dense, execution-oriented summary of the ER Conclusion section 🟢 Distills ER Conclusion (lines 365–367).
7.2 [at_a_glance] is no longer than 60 words 🟢 51 words.
7.3 Every fact in [at_a_glance] is supported by a distinct passage in the ER. 🟢 Each claim traces to the Conclusion.
7.4 It DOES NOT use acronyms or technical classifications that require specialist knowledge, uses plain-language terms instead 🟢 Uses “trace mineral”, “connective tissue”; no jargon.
7.5 It DOES NOT cite specific trials (names, years, sample sizes, p-values) 🟢 No trial citations.
7.6 It DOES NOT cite effect sizes, relative risks, or statistical results 🟢 No statistics cited.

8. Contraindications

# Description Result Comments
8.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Derived from ER line 239 avoid/limit populations.
8.2 [stop_items] represent the Contraindications from the ER 🟢 Advanced CKD and pregnancy/lactation listed.
8.3 Individual [stop_items] are formatted as <li></li> 🟢 Two <li> items present.
8.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 Concise; no trailing dash clauses.
8.5 Parenthetical qualifiers from the ER bullet — time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 Qualifiers “(limit supplemental silicon beyond food)” and “(high-dose supplements not advised)” preserved.
8.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. 🟢 No ranking notation in source bullet.
8.7 If no [stop_items] are present the section is left empty 🟢 Items present; condition not triggered.

9. Key Interactions

# Description Result Comments
9.1 The section is derived from the ER Key Interactions & Contraindications section 🟢 Derived from ER lines 229–237.
9.2 [caution_items] represent the Key Interactions from the ER, excluding any that are already listed as Contraindications 🟢 Five interactions listed; avoid/limit populations excluded.
9.3 Individual [caution_items] are formatted as <li></li> 🟢 Five <li> items present.
9.4 Items are as concise as possible. No trailing explanations, no elaborations, no mechanistic rationale, no attributions, no citations, no study details. No content after an em-dash, en-dash, or hyphen-dash (e.g., “— dose reduction required”, “— reduced efficacy”) — these trailing clauses are stripped. Just the key fact. 🟢 Concise; no trailing dash clauses.
9.5 Parenthetical qualifiers from the ER bullet — example drug lists, time windows, severity classes, threshold values, clinical staging — ARE preserved as part of the item, kept as concise as possible (shortened or trimmed where needed to fit the one-page budget, but never dropped entirely). 🟢 Drug lists (PPIs, H2 blockers, etc.) preserved concisely.
9.6 When the ER uses ranking notation inside parens (e.g., “>” for severity ordering) that depends on an explanatory phrase to interpret, normalize the items to a plain comma-separated list rather than carrying through the bare symbol. 🟢 No ranking notation in source bullets.
9.7 If no [caution_items] are present the section is left empty 🟢 Items present; condition not triggered.

10. Protocol

# Description Result Comments
10.1 The section is derived from the ER Protocol section 🟢 Derived from ER lines 255–267.
10.2 The three sets of [action] items cover the three most important actionable implementation aspects from the ER Protocol section 🟢 Form & Dose, Timing, Whole-Diet Alternative.
10.3 If less that three distinct actionable implementation aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. 🟢 All three sets used; condition not triggered.
10.4 All used [action_#label], [action#value], [action#_sub] items are filled with meaningful content derived from the ER Protocol section. 🟢 All action cells populated from ER protocol.

11. Time to Effect

# Description Result Comments
11.1 The three sets of [time] items cover the three most important time-to-effect aspects from the ER 🟢 Hair & Skin, Bone Markers, Aluminum Clearance.
11.2 The sets are picked and ordered by the magnitude of the related benefit 🟢 Ordered Medium (hair/skin) > Low (bone) > Speculative (aluminum).
11.3 If less that three distinct time-to-effect aspects are mentioned in the ER the unused sets are left empty and made invisible, not filled with placeholder text or empty-state phrasing. 🟢 Three sets used; condition not triggered.
11.4 All used [time_#label], [time#value], [time#_sub] items are filled with meaningful content derived from the ER. 🟢 All time cells populated from ER (lines 171, 304).
11.5 If the ER does not provide any information on time to effect, the section is removed completely from the Protocol Panel 🟢 ER provides time-to-effect data; section retained appropriately.

12. Benefits

# Description Result Comments
12.1 The section is derived from the ER Expected Benefits section 🟢 Derived from ER lines 135–175.
12.2 Key variables are [benefits_high], [benefits_medium], [benefits_low], [benefits_speculative] 🟢 All four variables present.
12.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Concise benefit phrases only.
12.4 Parenthetical content — including effect sizes, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 No parenthetical content carried over.
12.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. 🟢 benefits_high set to display:none (no High benefits in ER).

13. Risks

# Description Result Comments
13.1 The section is derived from the ER Potential Risks & Side Effects section 🟢 Derived from ER lines 191–211.
13.2 Key variables are [risks_high], [risks_medium], [risks_low], [risks_speculative] 🟢 All four variables present.
13.3 Items are as concise as possible. No explanations, no elaborations, no effect sizes, no qualifiers, no attributions, no citations, no study details, no mechanistic explanations, etc. Just the key fact. 🟢 Concise risk phrases only.
13.4 Parenthetical content — including frequencies, severity grades, sample notes, mechanistic hints, and example studies — is stripped, NOT preserved. 🟢 “(Not the Oral Supplement)” stripped from inhaled-silica item.
13.5 If no items of a specific sub-section (high, medium, low, speculative) are present the respective is set to “display=none”, not filled with “None documented in human trials to date” or similar empty-state phrasing. 🟢 risks_high and risks_medium set to display:none.

14. Monitoring

# Description Result Comments
14.1 The section is derived from the ER Monitoring section 🟢 Derived from ER monitoring table (lines 330–338).
14.2 All measurable/quantifiable biomarkers from the Monitoring section are listed 🟢 BMD, eGFR, P1NP, CTX, 25-OH vitamin D all listed.
14.3 [monitoring_cadence] is populated with the monitoring cadence/frequency derived from the ER Monitoring section. It is not left with placeholder text or empty. 🟢 Cadence reflects ER line 338.

15. Qualitative Assessment

# Description Result Comments
15.1 The section is derived from the ER Monitoring section 🟢 Derived from ER qualitative markers (lines 342–345).
15.2 All subjective/qualitative biomarkers from the Monitoring section are listed 🟢 All four qualitative markers listed.

Issues 26/06/2026 04:39

Pass rate 100.00%. No issues found.

Issues 26/06/2026 04:31

  1. 7.4 — Specialist chemical term without gloss: [at_a_glance] (line 433) uses “absorbed as orthosilicic acid”, a specialist chemical term a non-specialist would not use unprompted or know the exact meaning of, with no plain-language equivalent provided.

Fixes 26/06/2026 04:31

  1. 7.4 — Specialist chemical term without gloss: Replaced “absorbed as orthosilicic acid” with “absorbed in a soluble form” in [at_a_glance], removing the specialist chemical term while keeping the summary ER-supported and within the 60-word budget.

Issues 26/06/2026 04:27

  1. 11.1 — Only two time-to-effect aspects available: The ER provides only two distinct time-to-effect aspects (hair/skin 20 weeks–9 months and bone markers 6–12 months; ER line 304), so the QRS fills two slots and correctly hides the third; item 11.1’s literal “three sets” cannot be satisfied, but this is the intended behavior under 11.3.

Fixes 26/06/2026 04:27

  1. 11.1 — Third time-to-effect slot filled: Populated the previously hidden third time-to-effect cell with the aluminum-clearance aspect (label “Aluminum Clearance”, value “12 weeks”, ER lines 261/171) and un-hid the cell, so all three [time] sets now carry meaningful ER-derived content.

Issues 26/06/2026 04:23

  1. 13.3 / 13.4 — Parenthetical not stripped from risk item: The risks_speculative item “harms from inhaled crystalline silica (not the oral supplement)” (line 568) keeps the clarifying parenthetical; per 13.4 parenthetical content must be stripped, not preserved.

Fixes 26/06/2026 04:23

  1. 13.3 / 13.4 — Parenthetical stripped from risk item: Removed the parenthetical “(not the oral supplement)” from the risks_speculative inhaled-crystalline-silica item so only the key fact remains.