Tetradecylthioacetic acid is a lab-made fatty acid, sold online as a research chemical and fat-loss supplement, that pushes the liver and muscles to burn more ordinary fat. A few small, month-long human studies suggest a modest drop in harmful cholesterol and blood fats in people with abnormal blood fats; healthy volunteers showed no change within a week. Safety knowledge ends at four weeks; long-term risks are largely unknown. (Full Review)
| Marker | Target | Why |
|---|---|---|
| LDL cholesterol | <100 mg/dL (<2.6 mmol/L) | Main efficacy marker |
| ApoB | <80 mg/dL | Counts artery-clogging particles |
| Triglycerides | <100 mg/dL (<1.1 mmol/L) | Efficacy marker |
| HDL cholesterol | ≥50 mg/dL | Lipid balance |
| ALT / AST | ALT <25 U/L; AST <25 U/L | Liver safety |
| Creatinine / eGFR | eGFR >90 mL/min/1.73 m² | Kidney safety |
| CK | No established functional target; track change from own baseline | Muscle safety |
| Omega-3 index | ≥8% | Tracks omega-3 depletion |
| Fasting glucose / HbA1c | 70–90 mg/dL; HbA1c <5.4% | Metabolic effect |
| hs-CRP | <1.0 mg/L | Systemic inflammation |
| Methylmalonic acid | <0.27 µmol/L | B12 status check |
Cadence: Baseline before starting (after a 10–12-hour fast), 4–6 weeks after starting, then every 3 months while use continues, and once 4–8 weeks after stopping